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Design of First-in-Class Dual EZH2/HDAC Inhibitor: Biochemical Activity and Biological Evaluation in Cancer Cells.
Romanelli A, Stazi G, Fioravanti R, Zwergel C, Di Bello E, Pomella S, Perrone C, Battistelli C, Strippoli R, Tripodi M, Del Bufalo D, Rota R, Trisciuoglio D, Mai A, Valente S. Romanelli A, et al. Among authors: pomella s. ACS Med Chem Lett. 2020 Mar 19;11(5):977-983. doi: 10.1021/acsmedchemlett.0c00014. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435414 Free PMC article.
MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma.
Vella S, Pomella S, Leoncini PP, Colletti M, Conti B, Marquez VE, Strillacci A, Roma J, Gallego S, Milano GM, Capogrossi MC, Bertaina A, Ciarapica R, Rota R. Vella S, et al. Among authors: pomella s. Clin Epigenetics. 2015 Aug 6;7(1):82. doi: 10.1186/s13148-015-0107-z. eCollection 2015. Clin Epigenetics. 2015. PMID: 26251675 Free PMC article.
PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.
Gryder BE, Yohe ME, Chou HC, Zhang X, Marques J, Wachtel M, Schaefer B, Sen N, Song Y, Gualtieri A, Pomella S, Rota R, Cleveland A, Wen X, Sindiri S, Wei JS, Barr FG, Das S, Andresson T, Guha R, Lal-Nag M, Ferrer M, Shern JF, Zhao K, Thomas CJ, Khan J. Gryder BE, et al. Among authors: pomella s. Cancer Discov. 2017 Aug;7(8):884-899. doi: 10.1158/2159-8290.CD-16-1297. Epub 2017 Apr 26. Cancer Discov. 2017. PMID: 28446439 Free PMC article.
FAK Signaling in Rhabdomyosarcoma.
Perrone C, Pomella S, Cassandri M, Braghini MR, Pezzella M, Locatelli F, Rota R. Perrone C, et al. Among authors: pomella s. Int J Mol Sci. 2020 Nov 10;21(22):8422. doi: 10.3390/ijms21228422. Int J Mol Sci. 2020. PMID: 33182556 Free PMC article. Review.
Romidepsin (FK228) fails in counteracting the transformed phenotype of rhabdomyosarcoma cells but efficiently radiosensitizes, in vitro and in vivo, the alveolar phenotype subtype.
Rossetti A, Petragnano F, Milazzo L, Vulcano F, Macioce G, Codenotti S, Cassandri M, Pomella S, Cicchetti F, Fasciani I, Antinozzi C, Di Luigi L, Festuccia C, De Felice F, Vergine M, Fanzani A, Rota R, Maggio R, Polimeni A, Tombolini V, Gravina GL, Marampon F. Rossetti A, et al. Among authors: pomella s. Int J Radiat Biol. 2021;97(7):943-957. doi: 10.1080/09553002.2021.1928786. Epub 2021 Jun 4. Int J Radiat Biol. 2021. PMID: 33979259
MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells.
Cassandri M, Pomella S, Rossetti A, Petragnano F, Milazzo L, Vulcano F, Camero S, Codenotti S, Cicchetti F, Maggio R, Festuccia C, Gravina GL, Fanzani A, Megiorni F, Catanoso M, Marchese C, Tombolini V, Locatelli F, Rota R, Marampon F. Cassandri M, et al. Among authors: pomella s. Int J Mol Sci. 2021 Oct 1;22(19):10671. doi: 10.3390/ijms221910671. Int J Mol Sci. 2021. PMID: 34639012 Free PMC article.
Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects.
Romito I, Porru M, Braghini MR, Pompili L, Panera N, Crudele A, Gnani D, De Stefanis C, Scarsella M, Pomella S, Levi Mortera S, de Billy E, Conti AL, Marzano V, Putignani L, Vinciguerra M, Balsano C, Pastore A, Rota R, Tartaglia M, Leonetti C, Alisi A. Romito I, et al. Among authors: pomella s. J Exp Clin Cancer Res. 2021 Nov 16;40(1):364. doi: 10.1186/s13046-021-02154-8. J Exp Clin Cancer Res. 2021. PMID: 34784956 Free PMC article.
40 results