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Early administration of imatinib mesylate reduces plexiform neurofibroma tumor burden with durable results after drug discontinuation in a mouse model of neurofibromatosis type 1.
Armstrong AE, Rhodes SD, Smith A, Chen S, Bessler W, Ferguson MJ, Jiang L, Li X, Yuan J, Yang X, Yang FC, Robertson KA, Ingram DA, Blakeley JO, Clapp DW. Armstrong AE, et al. Among authors: yang fc, yang x. Pediatr Blood Cancer. 2020 Aug;67(8):e28372. doi: 10.1002/pbc.28372. Epub 2020 May 27. Pediatr Blood Cancer. 2020. PMID: 32459399 Free PMC article.
Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy.
Li X, Le Beau MM, Ciccone S, Yang FC, Freie B, Chen S, Yuan J, Hong P, Orazi A, Haneline LS, Clapp DW. Li X, et al. Among authors: yang fc. Blood. 2005 May 1;105(9):3465-71. doi: 10.1182/blood-2004-06-2483. Epub 2005 Jan 11. Blood. 2005. PMID: 15644418 Free PMC article.
462 results