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Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells.
Campbell C, McKenney PT, Konstantinovsky D, Isaeva OI, Schizas M, Verter J, Mai C, Jin WB, Guo CJ, Violante S, Ramos RJ, Cross JR, Kadaveru K, Hambor J, Rudensky AY. Campbell C, et al. Among authors: cross jr. Nature. 2020 May;581(7809):475-479. doi: 10.1038/s41586-020-2193-0. Epub 2020 Apr 15. Nature. 2020. PMID: 32461639 Free PMC article.
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.
Buffie CG, Bucci V, Stein RR, McKenney PT, Ling L, Gobourne A, No D, Liu H, Kinnebrew M, Viale A, Littmann E, van den Brink MR, Jenq RR, Taur Y, Sander C, Cross JR, Toussaint NC, Xavier JB, Pamer EG. Buffie CG, et al. Among authors: cross jr. Nature. 2015 Jan 8;517(7533):205-8. doi: 10.1038/nature13828. Epub 2014 Oct 22. Nature. 2015. PMID: 25337874 Free PMC article.
Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.
Monticelli LA, Buck MD, Flamar AL, Saenz SA, Tait Wojno ED, Yudanin NA, Osborne LC, Hepworth MR, Tran SV, Rodewald HR, Shah H, Cross JR, Diamond JM, Cantu E, Christie JD, Pearce EL, Artis D. Monticelli LA, et al. Among authors: cross jr. Nat Immunol. 2016 Jun;17(6):656-65. doi: 10.1038/ni.3421. Epub 2016 Apr 4. Nat Immunol. 2016. PMID: 27043409 Free PMC article.
Commensal bacteria make GPCR ligands that mimic human signalling molecules.
Cohen LJ, Esterhazy D, Kim SH, Lemetre C, Aguilar RR, Gordon EA, Pickard AJ, Cross JR, Emiliano AB, Han SM, Chu J, Vila-Farres X, Kaplitt J, Rogoz A, Calle PY, Hunter C, Bitok JK, Brady SF. Cohen LJ, et al. Among authors: cross jr. Nature. 2017 Sep 7;549(7670):48-53. doi: 10.1038/nature23874. Epub 2017 Aug 30. Nature. 2017. PMID: 28854168 Free PMC article.
Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations.
Intlekofer AM, Shih AH, Wang B, Nazir A, Rustenburg AS, Albanese SK, Patel M, Famulare C, Correa FM, Takemoto N, Durani V, Liu H, Taylor J, Farnoud N, Papaemmanuil E, Cross JR, Tallman MS, Arcila ME, Roshal M, Petsko GA, Wu B, Choe S, Konteatis ZD, Biller SA, Chodera JD, Thompson CB, Levine RL, Stein EM. Intlekofer AM, et al. Among authors: cross jr. Nature. 2018 Jul;559(7712):125-129. doi: 10.1038/s41586-018-0251-7. Epub 2018 Jun 27. Nature. 2018. PMID: 29950729 Free PMC article.
Stable Isotope Tracers for Metabolic Pathway Analysis.
Violante S, Berisa M, Thomas TH, Cross JR. Violante S, et al. Among authors: cross jr. Methods Mol Biol. 2019;1978:269-283. doi: 10.1007/978-1-4939-9236-2_17. Methods Mol Biol. 2019. PMID: 31119669
Microbiota-derived lantibiotic restores resistance against vancomycin-resistant Enterococcus.
Kim SG, Becattini S, Moody TU, Shliaha PV, Littmann ER, Seok R, Gjonbalaj M, Eaton V, Fontana E, Amoretti L, Wright R, Caballero S, Wang ZX, Jung HJ, Morjaria SM, Leiner IM, Qin W, Ramos RJJF, Cross JR, Narushima S, Honda K, Peled JU, Hendrickson RC, Taur Y, van den Brink MRM, Pamer EG. Kim SG, et al. Among authors: cross jr. Nature. 2019 Aug;572(7771):665-669. doi: 10.1038/s41586-019-1501-z. Epub 2019 Aug 21. Nature. 2019. PMID: 31435014 Free PMC article.
Vitamin B6 Addiction in Acute Myeloid Leukemia.
Chen CC, Li B, Millman SE, Chen C, Li X, Morris JP 4th, Mayle A, Ho YJ, Loizou E, Liu H, Qin W, Shah H, Violante S, Cross JR, Lowe SW, Zhang L. Chen CC, et al. Among authors: cross jr. Cancer Cell. 2020 Jan 13;37(1):71-84.e7. doi: 10.1016/j.ccell.2019.12.002. Cancer Cell. 2020. PMID: 31935373 Free PMC article.
210 results