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Page 1
MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer.
Augert A, Mathsyaraja H, Ibrahim AH, Freie B, Geuenich MJ, Cheng PF, Alibeckoff SP, Wu N, Hiatt JB, Basom R, Gazdar A, Sullivan LB, Eisenman RN, MacPherson D. Augert A, et al. Among authors: cheng pf. Cancer Cell. 2020 Jul 13;38(1):97-114.e7. doi: 10.1016/j.ccell.2020.04.016. Epub 2020 May 28. Cancer Cell. 2020. PMID: 32470392 Free PMC article.
Max deletion destabilizes MYC protein and abrogates Eµ-Myc lymphomagenesis.
Mathsyaraja H, Freie B, Cheng PF, Babaeva E, Catchpole JT, Janssens D, Henikoff S, Eisenman RN. Mathsyaraja H, et al. Among authors: cheng pf. Genes Dev. 2019 Sep 1;33(17-18):1252-1264. doi: 10.1101/gad.325878.119. Epub 2019 Aug 8. Genes Dev. 2019. PMID: 31395740 Free PMC article.
Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness.
Mathsyaraja H, Catchpole J, Freie B, Eastwood E, Babaeva E, Geuenich M, Cheng PF, Ayers J, Yu M, Wu N, Moorthi S, Poudel KR, Koehne A, Grady W, Houghton AM, Berger AH, Shiio Y, MacPherson D, Eisenman RN. Mathsyaraja H, et al. Among authors: cheng pf. Elife. 2021 Jul 8;10:e64212. doi: 10.7554/eLife.64212. Elife. 2021. PMID: 34236315 Free PMC article.
Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis.
Carroll PA, Diolaiti D, McFerrin L, Gu H, Djukovic D, Du J, Cheng PF, Anderson S, Ulrich M, Hurley JB, Raftery D, Ayer DE, Eisenman RN. Carroll PA, et al. Among authors: cheng pf. Cancer Cell. 2015 Feb 9;27(2):271-85. doi: 10.1016/j.ccell.2014.11.024. Epub 2015 Jan 29. Cancer Cell. 2015. PMID: 25640402 Free PMC article.
The glucose-sensing transcription factor MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis.
Carroll PA, Freie BW, Cheng PF, Kasinathan S, Gu H, Hedrich T, Dowdle JA, Venkataramani V, Ramani V, Wu X, Raftery D, Shendure J, Ayer DE, Muller CH, Eisenman RN. Carroll PA, et al. Among authors: cheng pf. PLoS Biol. 2021 Oct 20;19(10):e3001085. doi: 10.1371/journal.pbio.3001085. eCollection 2021 Oct. PLoS Biol. 2021. PMID: 34669700 Free PMC article.
Myc and Max homologs in Drosophila.
Gallant P, Shiio Y, Cheng PF, Parkhurst SM, Eisenman RN. Gallant P, et al. Among authors: cheng pf. Science. 1996 Nov 29;274(5292):1523-7. doi: 10.1126/science.274.5292.1523. Science. 1996. PMID: 8929412
Myc influences global chromatin structure.
Knoepfler PS, Zhang XY, Cheng PF, Gafken PR, McMahon SB, Eisenman RN. Knoepfler PS, et al. Among authors: cheng pf. EMBO J. 2006 Jun 21;25(12):2723-34. doi: 10.1038/sj.emboj.7601152. Epub 2006 May 25. EMBO J. 2006. PMID: 16724113 Free PMC article.
139 results