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Evolutionary engineering of a glycerol-3-phosphate dehydrogenase-negative, acetate-reducing Saccharomyces cerevisiae strain enables anaerobic growth at high glucose concentrations.
Guadalupe-Medina V, Metz B, Oud B, van Der Graaf CM, Mans R, Pronk JT, van Maris AJ. Guadalupe-Medina V, et al. Among authors: mans r. Microb Biotechnol. 2014 Jan;7(1):44-53. doi: 10.1111/1751-7915.12080. Epub 2013 Sep 4. Microb Biotechnol. 2014. PMID: 24004455 Free PMC article.
An alternative, arginase-independent pathway for arginine metabolism in Kluyveromyces lactis involves guanidinobutyrase as a key enzyme.
Romagnoli G, Verhoeven MD, Mans R, Fleury Rey Y, Bel-Rhlid R, van den Broek M, Seifar RM, Ten Pierick A, Thompson M, Müller V, Wahl SA, Pronk JT, Daran JM. Romagnoli G, et al. Among authors: mans r. Mol Microbiol. 2014 Jul;93(2):369-89. doi: 10.1111/mmi.12666. Epub 2014 Jun 23. Mol Microbiol. 2014. PMID: 24912400 Free PMC article.
Rewriting yeast central carbon metabolism for industrial isoprenoid production.
Meadows AL, Hawkins KM, Tsegaye Y, Antipov E, Kim Y, Raetz L, Dahl RH, Tai A, Mahatdejkul-Meadows T, Xu L, Zhao L, Dasika MS, Murarka A, Lenihan J, Eng D, Leng JS, Liu CL, Wenger JW, Jiang H, Chao L, Westfall P, Lai J, Ganesan S, Jackson P, Mans R, Platt D, Reeves CD, Saija PR, Wichmann G, Holmes VF, Benjamin K, Hill PW, Gardner TS, Tsong AE. Meadows AL, et al. Among authors: mans r. Nature. 2016 Sep 29;537(7622):694-697. doi: 10.1038/nature19769. Epub 2016 Sep 21. Nature. 2016. PMID: 27654918
93 results