Wu H - Search Results

1

Gain-of-function mutations in CARD11 promote enhanced aggregation and idiosyncratic signalosome assembly.

Stinson JR, Dorjbal B, McDaniel DP, David L, Wu H, Snow AL. Stinson JR, et al. Among authors: wu h. Cell Immunol. 2020 Jul;353:104129. doi: 10.1016/j.cellimm.2020.104129. Epub 2020 May 14. Cell Immunol. 2020. PMID: 32473470 Free PMC article.

2

Structural basis of signal transduction in the TNF receptor superfamily.

Li J, Yin Q, Wu H. Li J, et al. Among authors: wu h. Adv Immunol. 2013;119:135-53. doi: 10.1016/B978-0-12-407707-2.00005-9. Adv Immunol. 2013. PMID: 23886067 Free PMC article. Review.

3

Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly.

Qiao Q, Yang C, Zheng C, Fontán L, David L, Yu X, Bracken C, Rosen M, Melnick A, Egelman EH, Wu H. Qiao Q, et al. Among authors: wu h. Mol Cell. 2013 Sep 26;51(6):766-79. doi: 10.1016/j.molcel.2013.08.032. Mol Cell. 2013. PMID: 24074955 Free PMC article.

4

The CBM signalosome: potential therapeutic target for aggressive lymphoma?

Yang C, David L, Qiao Q, Damko E, Wu H. Yang C, et al. Among authors: wu h. Cytokine Growth Factor Rev. 2014 Apr;25(2):175-83. doi: 10.1016/j.cytogfr.2013.12.008. Epub 2013 Dec 24. Cytokine Growth Factor Rev. 2014. PMID: 24411492 Free PMC article. Review.

5

Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.

Zhang L, Chen S, Ruan J, Wu J, Tong AB, Yin Q, Li Y, David L, Lu A, Wang WL, Marks C, Ouyang Q, Zhang X, Mao Y, Wu H. Zhang L, et al. Among authors: wu h, wu j. Science. 2015 Oct 23;350(6259):404-9. doi: 10.1126/science.aac5789. Epub 2015 Oct 8. Science. 2015. PMID: 26449474 Free PMC article.

6

Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome.

David L, Li Y, Ma J, Garner E, Zhang X, Wu H. David L, et al. Among authors: wu h. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1499-1504. doi: 10.1073/pnas.1721967115. Epub 2018 Jan 30. Proc Natl Acad Sci U S A. 2018. PMID: 29382759 Free PMC article.

7

Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization.

Hauseman ZJ, Harvey EP, Newman CE, Wales TE, Bucci JC, Mintseris J, Schweppe DK, David L, Fan L, Cohen DT, Herce HD, Mourtada R, Ben-Nun Y, Bloch NB, Hansen SB, Wu H, Gygi SP, Engen JR, Walensky LD. Hauseman ZJ, et al. Among authors: wu h. Mol Cell. 2020 Jul 2;79(1):68-83.e7. doi: 10.1016/j.molcel.2020.05.029. Epub 2020 Jun 12. Mol Cell. 2020. PMID: 32533918 Free PMC article.

8

Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.

Robert Hollingsworth L, David L, Li Y, Griswold AR, Ruan J, Sharif H, Fontana P, Orth-He EL, Fu TM, Bachovchin DA, Wu H. Robert Hollingsworth L, et al. Among authors: wu h. Nat Commun. 2021 Jan 8;12(1):189. doi: 10.1038/s41467-020-20320-y. Nat Commun. 2021. PMID: 33420033 Free PMC article.

9

NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation.

Andreeva L, David L, Rawson S, Shen C, Pasricha T, Pelegrin P, Wu H. Andreeva L, et al. Among authors: wu h. Cell. 2021 Dec 22;184(26):6299-6312.e22. doi: 10.1016/j.cell.2021.11.011. Epub 2021 Dec 2. Cell. 2021. PMID: 34861190 Free PMC article.

10

BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL.

Xia M, David L, Teater M, Gutierrez J, Wang X, Meydan C, Lytle A, Slack GW, Scott DW, Morin RD, Onder O, Elenitoba-Johnson KSJ, Zamponi N, Cerchietti L, Lu T, Philippar U, Fontan L, Wu H, Melnick AM. Xia M, et al. Among authors: wu h. Cancer Discov. 2022 Aug 5;12(8):1922-1941. doi: 10.1158/2159-8290.CD-21-1566. Cancer Discov. 2022. PMID: 35658124 Free PMC article.

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