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23 results

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Page 1
Introducing of potent cytotoxic novel 2-(aroylamino)cinnamamide derivatives against colon cancer mediated by dual apoptotic signal activation and oxidative stress.
Omar AM, El-Araby ME, Abdelghany TM, Safo MK, Ahmed MH, Boothello R, Patel BB, Abdel-Bakky MS, Malebari AM, Ahmed HEA, Elhaggar RS. Omar AM, et al. Among authors: elhaggar rs. Bioorg Chem. 2020 Aug;101:103953. doi: 10.1016/j.bioorg.2020.103953. Epub 2020 May 25. Bioorg Chem. 2020. PMID: 32474179
Development of 2-oindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells.
Eldehna WM, Abo-Ashour MF, Al-Warhi T, Al-Rashood ST, Alharbi A, Ayyad RR, Al-Khayal K, Abdulla M, Abdel-Aziz HA, Ahmad R, El-Haggar R. Eldehna WM, et al. J Enzyme Inhib Med Chem. 2021 Dec;36(1):319-328. doi: 10.1080/14756366.2020.1862100. J Enzyme Inhib Med Chem. 2021. PMID: 33345633 Free PMC article.
Development of isatin-thiazolo[3,2-a]benzimidazole hybrids as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological and molecular dynamics investigations.
Eldehna WM, El Hassab MA, Abo-Ashour MF, Al-Warhi T, Elaasser MM, Safwat NA, Suliman H, Ahmed MF, Al-Rashood ST, Abdel-Aziz HA, El-Haggar R. Eldehna WM, et al. Bioorg Chem. 2021 May;110:104748. doi: 10.1016/j.bioorg.2021.104748. Epub 2021 Feb 18. Bioorg Chem. 2021. PMID: 33684714
Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates via a 2-Thioacetamido linker as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers.
Eissa IH, El-Haggar R, Dahab MA, Ahmed MF, Mahdy HA, Alsantali RI, Elwan A, Masurier N, Fatahala SS. Eissa IH, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1587-1599. doi: 10.1080/14756366.2022.2081844. J Enzyme Inhib Med Chem. 2022. PMID: 35637622 Free PMC article.
23 results