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A replication-competent late liver stage-attenuated human malaria parasite.
Goswami D, Betz W, Locham NK, Parthiban C, Brager C, Schäfer C, Camargo N, Nguyen T, Kennedy SY, Murphy SC, Vaughan AM, Kappe SH. Goswami D, et al. Among authors: schafer c. JCI Insight. 2020 Jul 9;5(13):e135589. doi: 10.1172/jci.insight.135589. JCI Insight. 2020. PMID: 32484795 Free PMC article.
Assessing drug efficacy against Plasmodium falciparum liver stages in vivo.
Flannery EL, Foquet L, Chuenchob V, Fishbaugher M, Billman Z, Navarro MJ, Betz W, Olsen TM, Lee J, Camargo N, Nguyen T, Schafer C, Sack BK, Wilson EM, Saunders J, Bial J, Campo B, Charman SA, Murphy SC, Phillips MA, Kappe SH, Mikolajczak SA. Flannery EL, et al. Among authors: schafer c. JCI Insight. 2018 Jan 11;3(1):e92587. doi: 10.1172/jci.insight.92587. eCollection 2018 Jan 11. JCI Insight. 2018. PMID: 29321371 Free PMC article.
Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of Blood Stage Inhibitory Antibodies (Reticulocyte-Binding Protein Homolog 5) In Vivo.
Foquet L, Schafer C, Minkah NK, Alanine DGW, Flannery EL, Steel RWJ, Sack BK, Camargo N, Fishbaugher M, Betz W, Nguyen T, Billman ZP, Wilson EM, Bial J, Murphy SC, Draper SJ, Mikolajczak SA, Kappe SHI. Foquet L, et al. Among authors: schafer c. Front Immunol. 2018 Mar 14;9:524. doi: 10.3389/fimmu.2018.00524. eCollection 2018. Front Immunol. 2018. PMID: 29593746 Free PMC article.
A Humanized Mouse Model for Plasmodium vivax to Test Interventions that Block Liver Stage to Blood Stage Transition and Blood Stage Infection.
Schäfer C, Roobsoong W, Kangwanrangsan N, Bardelli M, Rawlinson TA, Dambrauskas N, Trakhimets O, Parthiban C, Goswami D, Reynolds LM, Kennedy SY, Flannery EL, Murphy SC, Sather DN, Draper SJ, Sattabongkot J, Mikolajczak SA, Kappe SHI. Schäfer C, et al. iScience. 2020 Aug 21;23(8):101381. doi: 10.1016/j.isci.2020.101381. Epub 2020 Jul 18. iScience. 2020. PMID: 32739836 Free PMC article.
Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine.
Flannery EL, Kangwanrangsan N, Chuenchob V, Roobsoong W, Fishbaugher M, Zhou K, Billman ZP, Martinson T, Olsen TM, Schäfer C, Campo B, Murphy SC, Mikolajczak SA, Kappe SHI, Sattabongkot J. Flannery EL, et al. Among authors: schafer c. Mol Ther Methods Clin Dev. 2022 Aug 2;26:427-440. doi: 10.1016/j.omtm.2022.07.016. eCollection 2022 Sep 8. Mol Ther Methods Clin Dev. 2022. PMID: 36092359 Free PMC article.
Mass Spectrometry Identification of Biomarkers in Extracellular Vesicles From Plasmodium vivax Liver Hypnozoite Infections.
Gualdrón-López M, Díaz-Varela M, Zanghi G, Aparici-Herraiz I, Steel RWJ, Schäfer C, Cuscó P, Chuenchob V, Kangwangransan N, Billman ZP, Olsen TM, González JR, Roobsoong W, Sattabongkot J, Murphy SC, Mikolajczak SA, Borràs E, Sabidó E, Fernandez-Becerra C, Flannery EL, Kappe SHI, Del Portillo HA. Gualdrón-López M, et al. Among authors: schafer c. Mol Cell Proteomics. 2022 Oct;21(10):100406. doi: 10.1016/j.mcpro.2022.100406. Epub 2022 Aug 24. Mol Cell Proteomics. 2022. PMID: 36030044 Free PMC article.
982 results