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Page 1
Caveolin-1 regulates medium spiny neuron structural and functional plasticity.
Eisinger KRT, Chapp AD, Swanson SP, Tam D, Lopresti NM, Larson EB, Thomas MJ, Lanier LM, Mermelstein PG. Eisinger KRT, et al. Among authors: swanson sp. Psychopharmacology (Berl). 2020 Sep;237(9):2673-2684. doi: 10.1007/s00213-020-05564-2. Epub 2020 Jun 2. Psychopharmacology (Berl). 2020. PMID: 32488350 Free PMC article.
Antagonism of the brain P2X7 ion channel attenuates repeated social defeat induced microglia reactivity, monocyte recruitment and anxiety-like behavior in male mice.
Biltz RG, Swanson SP, Draime N, Davis AC, Yin W, Goodman EJ, Gallagher NR, Bhattacharya A, Sheridan JF, Godbout JP. Biltz RG, et al. Among authors: swanson sp. Brain Behav Immun. 2024 Jan;115:356-373. doi: 10.1016/j.bbi.2023.10.011. Epub 2023 Oct 31. Brain Behav Immun. 2024. PMID: 37914101 Free PMC article.
Unique brain endothelial profiles activated by social stress promote cell adhesion, prostaglandin E2 signaling, hypothalamic-pituitary-adrenal axis modulation, and anxiety.
Yin W, Swanson SP, Biltz RG, Goodman EJ, Gallagher NR, Sheridan JF, Godbout JP. Yin W, et al. Among authors: swanson sp. Neuropsychopharmacology. 2022 Dec;47(13):2271-2282. doi: 10.1038/s41386-022-01434-x. Epub 2022 Sep 14. Neuropsychopharmacology. 2022. PMID: 36104533 Free PMC article.
N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes.
Fell MJ, Witkin JM, Falcone JF, Katner JS, Perry KW, Hart J, Rorick-Kehn L, Overshiner CD, Rasmussen K, Chaney SF, Benvenga MJ, Li X, Marlow DL, Thompson LK, Luecke SK, Wafford KA, Seidel WF, Edgar DM, Quets AT, Felder CC, Wang X, Heinz BA, Nikolayev A, Kuo MS, Mayhugh D, Khilevich A, Zhang D, Ebert PJ, Eckstein JA, Ackermann BL, Swanson SP, Catlow JT, Dean RA, Jackson K, Tauscher-Wisniewski S, Marek GJ, Schkeryantz JM, Svensson KA. Fell MJ, et al. Among authors: swanson sp. J Pharmacol Exp Ther. 2011 Jan;336(1):165-77. doi: 10.1124/jpet.110.172957. Epub 2010 Oct 14. J Pharmacol Exp Ther. 2011. PMID: 20947638
The 5-hydroxytryptamine2A receptor antagonist R-(+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-4-piperidinemethanol (M100907) attenuates impulsivity after both drug-induced disruption (dizocilpine) and enhancement (antidepressant drugs) of differential-reinforcement-of-low-rate 72-s behavior in the rat.
Ardayfio PA, Benvenga MJ, Chaney SF, Love PL, Catlow J, Swanson SP, Marek GJ. Ardayfio PA, et al. Among authors: swanson sp. J Pharmacol Exp Ther. 2008 Dec;327(3):891-7. doi: 10.1124/jpet.108.143370. Epub 2008 Sep 4. J Pharmacol Exp Ther. 2008. PMID: 18772320
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