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Topoisomerase III-ß is required for efficient replication of positive-sense RNA viruses.
Prasanth KR, Hirano M, Fagg WS, McAnarney ET, Shan C, Xie X, Hage A, Pietzsch CA, Bukreyev A, Rajsbaum R, Shi PY, Bedford MT, Bradrick SS, Menachery V, Garcia-Blanco MA. Prasanth KR, et al. Among authors: pietzsch ca. bioRxiv [Preprint]. 2020 Mar 27:2020.03.24.005900. doi: 10.1101/2020.03.24.005900. bioRxiv. 2020. Update in: Antiviral Res. 2020 Oct;182:104874. doi: 10.1016/j.antiviral.2020.104874. PMID: 32511318 Free PMC article. Updated. Preprint.
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.
Rialdi A, Campisi L, Zhao N, Lagda AC, Pietzsch C, Ho JSY, Martinez-Gil L, Fenouil R, Chen X, Edwards M, Metreveli G, Jordan S, Peralta Z, Munoz-Fontela C, Bouvier N, Merad M, Jin J, Weirauch M, Heinz S, Benner C, van Bakel H, Basler C, García-Sastre A, Bukreyev A, Marazzi I. Rialdi A, et al. Science. 2016 May 27;352(6289):aad7993. doi: 10.1126/science.aad7993. Epub 2016 Apr 28. Science. 2016. PMID: 27127234 Free PMC article.
Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.
Luthra P, Naidoo J, Pietzsch CA, De S, Khadka S, Anantpadma M, Williams CG, Edwards MR, Davey RA, Bukreyev A, Ready JM, Basler CF. Luthra P, et al. Among authors: pietzsch ca. Antiviral Res. 2018 Oct;158:288-302. doi: 10.1016/j.antiviral.2018.08.012. Epub 2018 Aug 23. Antiviral Res. 2018. PMID: 30144461 Free PMC article.
Protein Phosphatase 1-Targeting Small-Molecule C31 Inhibits Ebola Virus Replication.
Ammosova T, Pietzsch CA, Saygideger Y, Ilatovsky A, Lin X, Ivanov A, Kumari N, Jerebtsova M, Kulkarni A, Petukhov M, Üren A, Bukreyev A, Nekhai S. Ammosova T, et al. Among authors: pietzsch ca. J Infect Dis. 2018 Nov 22;218(suppl_5):S627-S635. doi: 10.1093/infdis/jiy422. J Infect Dis. 2018. PMID: 30169869 Free PMC article.
26 results