El-Awady R - Search Results

1

Multi-omics analysis revealed significant metabolic changes in brain cancer cells treated with paclitaxel and/or topotecan.

Semreen AM, Alsoud LO, Semreen MH, Ahmed M, Al-Hroub HM, El-Awady R, Ramadan WS, Abuhelwa A, Bustanji Y, Soares NC, Alzoubi KH. Semreen AM, et al. Among authors: el awady r. Heliyon. 2024 Oct 18;10(21):e39420. doi: 10.1016/j.heliyon.2024.e39420. eCollection 2024 Nov 15. Heliyon. 2024. PMID: 39524752 Free PMC article.

2

Combining lavendustin C and 5-arylidenethiazolin-4-one-based pharmacophores toward multitarget anticancer hybrids.

Othman SA, Abou-Ghadir OF, Menon V, Ramadan WS, Mostafa YA, El-Awady R, Abdu-Allah HHM. Othman SA, et al. Among authors: el awady r. Bioorg Chem. 2024 Dec;153:107884. doi: 10.1016/j.bioorg.2024.107884. Epub 2024 Oct 12. Bioorg Chem. 2024. PMID: 39423773

3

Impact of HDAC6-mediated progesterone receptor expression on the response of breast cancer cells to hormonal therapy.

Ramadan WS, Alseksek RK, Mouffak S, Talaat IM, Saber-Ayad MM, Menon V, Ilce BY, El-Awady R. Ramadan WS, et al. Among authors: el awady r. Eur J Pharmacol. 2024 Nov 15;983:177001. doi: 10.1016/j.ejphar.2024.177001. Epub 2024 Sep 14. Eur J Pharmacol. 2024. PMID: 39284403

4

Tetrahydrocarbazoles incorporating 5-arylidene-4-thiazolinones as potential antileukemia and antilymphoma targeting tyrosine kinase and tubulin polymerase enzymes: Design, synthesis, structural, biological and molecular docking studies.

Ali BS, Mohammed AF, Kariuki BM, El-Awady R, H M Abdu-Allah H. Ali BS, et al. Among authors: el awady r. Bioorg Chem. 2024 Dec;153:107817. doi: 10.1016/j.bioorg.2024.107817. Epub 2024 Sep 10. Bioorg Chem. 2024. PMID: 39278066

5

Transcriptomic analysis of MCF7 breast cancer cells treated with MGBs reveals a profound inhibition of estrogen receptor genes.

Alniss HY, Saber-Ayad MM, Ramadan WS, Manasa Bhamidimarri P, Msallam YA, Al-Jubeh HM, Ravi A, Menon V, Hamoudi R, El-Awady R. Alniss HY, et al. Among authors: el awady r. Bioorg Chem. 2024 Oct;151:107680. doi: 10.1016/j.bioorg.2024.107680. Epub 2024 Jul 27. Bioorg Chem. 2024. PMID: 39084151

6

Decoding host cell interaction- and fluconazole-induced metabolic alterations and drug resistance in Candida auris.

Ismail SHH, Hamdy R, Altaie AM, Fayed B, Dakalbab S, El-Awady R, Soliman SSM. Ismail SHH, et al. Among authors: el awady r. Mycologia. 2024 Sep-Oct;116(5):673-693. doi: 10.1080/00275514.2024.2363730. Epub 2024 Jul 18. Mycologia. 2024. PMID: 39024116

7

Author Correction: Targeting the DYRK1A kinase prevents cancer progression and metastasis and promotes cancer cells response to G1/S targeting chemotherapy drugs.

Laham AJ, El-Awady R, Saber-Ayad M, Wang N, Yan G, Boudreault J, Ali S, Lebrun JJ. Laham AJ, et al. Among authors: el awady r. NPJ Precis Oncol. 2024 Jul 8;8(1):141. doi: 10.1038/s41698-024-00628-4. NPJ Precis Oncol. 2024. PMID: 38977910 Free PMC article. No abstract available.

8

Targeting the DYRK1A kinase prevents cancer progression and metastasis and promotes cancer cells response to G1/S targeting chemotherapy drugs.

Laham AJ, El-Awady R, Saber-Ayad M, Wang N, Yan G, Boudreault J, Ali S, Lebrun JJ. Laham AJ, et al. Among authors: el awady r. NPJ Precis Oncol. 2024 Jun 5;8(1):128. doi: 10.1038/s41698-024-00614-w. NPJ Precis Oncol. 2024. PMID: 38839871 Free PMC article.

9

Spectroscopic, biochemical and computational studies of bioactive DNA minor groove binders targeting 5'-WGWWCW-3' motif.

Alniss HY, Kemp BM, Holmes E, Hoffmann J, Ploch RM, Ramadan WS, Msallam YA, Al-Jubeh HM, Madkour MM, Celikkaya BC, Scott FJ, El-Awady R, Parkinson JA. Alniss HY, et al. Among authors: el awady r. Bioorg Chem. 2024 Jul;148:107414. doi: 10.1016/j.bioorg.2024.107414. Epub 2024 May 8. Bioorg Chem. 2024. PMID: 38733748 Free article.

10

Deciphering the interplay of histone post-translational modifications in cancer: Co-targeting histone modulators for precision therapy.

Kawaf RR, Ramadan WS, El-Awady R. Kawaf RR, et al. Among authors: el awady r. Life Sci. 2024 Jun 1;346:122639. doi: 10.1016/j.lfs.2024.122639. Epub 2024 Apr 13. Life Sci. 2024. PMID: 38615747 Review.

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