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Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach.
Lorthiois E, Roache J, Barnes-Seeman D, Altmann E, Hassiepen U, Turner G, Duvadie R, Hornak V, Karki RG, Schiering N, Weihofen WA, Perruccio F, Calhoun A, Fazal T, Dedic D, Durand C, Dussauge S, Fettis K, Tritsch F, Dentel C, Druet A, Liu D, Kirman L, Lachal J, Namoto K, Bevan D, Mo R, Monnet G, Muller L, Zessis R, Huang X, Lindsley L, Currie T, Chiu YH, Fridrich C, Delgado P, Wang S, Hollis-Symynkywicz M, Berghausen J, Williams E, Liu H, Liang G, Kim H, Hoffmann P, Hein A, Ramage P, D'Arcy A, Harlfinger S, Renatus M, Ruedisser S, Feldman D, Elliott J, Sedrani R, Maibaum J, Adams CM. Lorthiois E, et al. Among authors: feldman d, d arcy a. J Med Chem. 2020 Aug 13;63(15):8088-8113. doi: 10.1021/acs.jmedchem.0c00279. Epub 2020 Jul 21. J Med Chem. 2020. PMID: 32551603
MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans.
Koch AW, Schiering N, Melkko S, Ewert S, Salter J, Zhang Y, McCormack P, Yu J, Huang X, Chiu YH, Chen Z, Schleeger S, Horny G, DiPetrillo K, Muller L, Hein A, Villard F, Scharenberg M, Ramage P, Hassiepen U, Côté S, DeGagne J, Krantz C, Eder J, Stoll B, Kulmatycki K, Feldman DL, Hoffmann P, Basson CT, Frost RJA, Khder Y. Koch AW, et al. Blood. 2019 Mar 28;133(13):1507-1516. doi: 10.1182/blood-2018-10-880849. Epub 2019 Jan 28. Blood. 2019. PMID: 30692123 Free article.
Carotid Artery Stenting.
Li J, Feldman DN, Klein AJ, Malas MB, Metzger DC, Parikh SA, Roubin GS, Soukas PA, Tsai S, Gray WA; Members of the SCAI 2024 Think Tank Peripheral Consortium; Bliss C, Brounstein K, Canorea-Vega F, Dean R, Donnelly G, Farrel L, Gleason S, Hughes C, Kohler M, McGonigle J, Minor DJ, Newell A, O'Hara J, Perez O, Rangwala N, Sachar R, Williams J. Li J, et al. Among authors: feldman dn. J Soc Cardiovasc Angiogr Interv. 2024 Dec 19;3(12):102435. doi: 10.1016/j.jscai.2024.102435. eCollection 2024 Dec. J Soc Cardiovasc Angiogr Interv. 2024. PMID: 39807228 Free PMC article. No abstract available.
Excitons in the fractional quantum Hall effect.
Zhang NJ, Nguyen RQ, Batra N, Liu X, Watanabe K, Taniguchi T, Feldman DE, Li JIA. Zhang NJ, et al. Among authors: feldman de. Nature. 2025 Jan;637(8045):327-332. doi: 10.1038/s41586-024-08274-3. Epub 2025 Jan 8. Nature. 2025. PMID: 39780005
1,943 results