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Absence of QTc prolongation in a thorough QT study with imeglimin, a first in class oral agent for type 2 diabetes mellitus.
Eur J Clin Pharmacol. 2020 Oct;76(10):1393-1400. doi: 10.1007/s00228-020-02929-6. Epub 2020 Jun 18.
Eur J Clin Pharmacol. 2020.
PMID: 32556539
Clinical Trial.
Imeglimin Does Not Induce Clinically Relevant Pharmacokinetic Interactions When Combined with Either Metformin or Sitagliptin in Healthy Subjects.
Fouqueray P, Perrimond-Dauchy S, Bolze S.
Fouqueray P, et al. Among authors: perrimond dauchy s.
Clin Pharmacokinet. 2020 Oct;59(10):1261-1271. doi: 10.1007/s40262-020-00886-y.
Clin Pharmacokinet. 2020.
PMID: 32270440
Clinical Trial.
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Lack of Drug-Drug Interaction Between Cimetidine, a Renal Transporter Inhibitor, and Imeglimin, a Novel Oral Antidiabetic Drug, in Healthy Volunteers.
Chevalier C, Perrimond-Dauchy S, Dubourg J, Fouqueray P, Bolze S.
Chevalier C, et al. Among authors: perrimond dauchy s.
Eur J Drug Metab Pharmacokinet. 2020 Dec;45(6):725-733. doi: 10.1007/s13318-020-00642-4.
Eur J Drug Metab Pharmacokinet. 2020.
PMID: 32860624
Clinical Trial.
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