Ruckwardt TJ - Search Results

1

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness.

Corbett KS, Edwards D, Leist SR, Abiona OM, Boyoglu-Barnum S, Gillespie RA, Himansu S, Schäfer A, Ziwawo CT, DiPiazza AT, Dinnon KH, Elbashir SM, Shaw CA, Woods A, Fritch EJ, Martinez DR, Bock KW, Minai M, Nagata BM, Hutchinson GB, Bahl K, Garcia-Dominguez D, Ma L, Renzi I, Kong WP, Schmidt SD, Wang L, Zhang Y, Stevens LJ, Phung E, Chang LA, Loomis RJ, Altaras NE, Narayanan E, Metkar M, Presnyak V, Liu C, Louder MK, Shi W, Leung K, Yang ES, West A, Gully KL, Wang N, Wrapp D, Doria-Rose NA, Stewart-Jones G, Bennett H, Nason MC, Ruckwardt TJ, McLellan JS, Denison MR, Chappell JD, Moore IN, Morabito KM, Mascola JR, Baric RS, Carfi A, Graham BS. Corbett KS, et al. Among authors: ruckwardt tj. bioRxiv [Preprint]. 2020 Jun 11:2020.06.11.145920. doi: 10.1101/2020.06.11.145920. bioRxiv. 2020. Update in: Nature. 2020 Oct;586(7830):567-571. doi: 10.1038/s41586-020-2622-0 PMID: 32577634 Free PMC article. Updated. Preprint.

2

Relative dominance of epitope-specific CD8+ T cell responses in an F1 hybrid mouse model of respiratory syncytial virus infection.

Rutigliano JA, Ruckwardt TJ, Martin JE, Graham BS. Rutigliano JA, et al. Among authors: ruckwardt tj. Virology. 2007 Jun 5;362(2):314-9. doi: 10.1016/j.virol.2006.12.023. Epub 2007 Feb 2. Virology. 2007. PMID: 17275872 Free PMC article.

3

Regulatory T cells promote early influx of CD8+ T cells in the lungs of respiratory syncytial virus-infected mice and diminish immunodominance disparities.

Ruckwardt TJ, Bonaparte KL, Nason MC, Graham BS. Ruckwardt TJ, et al. J Virol. 2009 Apr;83(7):3019-28. doi: 10.1128/JVI.00036-09. Epub 2009 Jan 19. J Virol. 2009. PMID: 19153229 Free PMC article.

4

Characterization of respiratory syncytial virus M- and M2-specific CD4 T cells in a murine model.

Liu J, Ruckwardt TJ, Chen M, Johnson TR, Graham BS. Liu J, et al. Among authors: ruckwardt tj. J Virol. 2009 May;83(10):4934-41. doi: 10.1128/JVI.02140-08. Epub 2009 Mar 4. J Virol. 2009. PMID: 19264776 Free PMC article.

5

Epitope-specific regulatory CD4 T cells reduce virus-induced illness while preserving CD8 T-cell effector function at the site of infection.

Liu J, Ruckwardt TJ, Chen M, Nicewonger JD, Johnson TR, Graham BS. Liu J, et al. Among authors: ruckwardt tj. J Virol. 2010 Oct;84(20):10501-9. doi: 10.1128/JVI.00963-10. Epub 2010 Aug 4. J Virol. 2010. PMID: 20686045 Free PMC article.

6

Responses against a subdominant CD8+ T cell epitope protect against immunopathology caused by a dominant epitope.

Ruckwardt TJ, Luongo C, Malloy AM, Liu J, Chen M, Collins PL, Graham BS. Ruckwardt TJ, et al. J Immunol. 2010 Oct 15;185(8):4673-80. doi: 10.4049/jimmunol.1001606. Epub 2010 Sep 10. J Immunol. 2010. PMID: 20833834 Free PMC article.

7

T Cell receptor clonotype influences epitope hierarchy in the CD8+ T cell response to respiratory syncytial virus infection.

Billam P, Bonaparte KL, Liu J, Ruckwardt TJ, Chen M, Ryder AB, Wang R, Dash P, Thomas PG, Graham BS. Billam P, et al. Among authors: ruckwardt tj. J Biol Chem. 2011 Feb 11;286(6):4829-41. doi: 10.1074/jbc.M110.191437. Epub 2010 Nov 30. J Biol Chem. 2011. PMID: 21118816 Free PMC article.

8

Neonatal CD8 T-cell hierarchy is distinct from adults and is influenced by intrinsic T cell properties in respiratory syncytial virus infected mice.

Ruckwardt TJ, Malloy AM, Gostick E, Price DA, Dash P, McClaren JL, Thomas PG, Graham BS. Ruckwardt TJ, et al. PLoS Pathog. 2011 Dec;7(12):e1002377. doi: 10.1371/journal.ppat.1002377. Epub 2011 Dec 1. PLoS Pathog. 2011. PMID: 22144888 Free PMC article.

9

Quantitative and qualitative deficits in neonatal lung-migratory dendritic cells impact the generation of the CD8+ T cell response.

Ruckwardt TJ, Malloy AM, Morabito KM, Graham BS. Ruckwardt TJ, et al. PLoS Pathog. 2014 Feb 13;10(2):e1003934. doi: 10.1371/journal.ppat.1003934. eCollection 2014 Feb. PLoS Pathog. 2014. PMID: 24550729 Free PMC article.

10

CD8+ TCR transgenic strains expressing public versus private TCR targeting the respiratory syncytial virus K(d)M2(82-90) epitope demonstrate similar functional profiles.

Bar-Haim E, Erez N, Malloy AM, Graham BS, Ruckwardt TJ. Bar-Haim E, et al. Among authors: ruckwardt tj. PLoS One. 2014 Jun 4;9(6):e99249. doi: 10.1371/journal.pone.0099249. eCollection 2014. PLoS One. 2014. PMID: 24897427 Free PMC article.

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