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A small-molecule ARTS mimetic promotes apoptosis through degradation of both XIAP and Bcl-2.
Cell Death Dis. 2020 Jun 25;11(6):483. doi: 10.1038/s41419-020-2670-2.
Cell Death Dis. 2020.
PMID: 32587235
Free PMC article.
Degradation of Bcl-2 by XIAP and ARTS Promotes Apoptosis.
Edison N, Curtz Y, Paland N, Mamriev D, Chorubczyk N, Haviv-Reingewertz T, Kfir N, Morgenstern D, Kupervaser M, Kagan J, Kim HT, Larisch S.
Edison N, et al. Among authors: mamriev d.
Cell Rep. 2017 Oct 10;21(2):442-454. doi: 10.1016/j.celrep.2017.09.052.
Cell Rep. 2017.
PMID: 29020630
Free PMC article.
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Another one bites the dust; ARTS enables degradation of Bcl-2 by XIAP.
Mamriev D, Larisch S.
Mamriev D, et al.
Mol Cell Oncol. 2018 Jun 25;5(4):e1441630. doi: 10.1080/23723556.2018.1441630. eCollection 2018.
Mol Cell Oncol. 2018.
PMID: 30250908
Free PMC article.
Review.
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