Castillejo-López C - Search Results

1

Proof-of-concept for CRISPR/Cas9 gene editing in human preadipocytes: Deletion of FKBP5 and PPARG and effects on adipocyte differentiation and metabolism.

Kamble PG, Hetty S, Vranic M, Almby K, Castillejo-López C, Abalo XM, Pereira MJ, Eriksson JW. Kamble PG, et al. Among authors: castillejo lopez c. Sci Rep. 2020 Jun 29;10(1):10565. doi: 10.1038/s41598-020-67293-y. Sci Rep. 2020. PMID: 32601291 Free PMC article.

2

Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance.

Nowak C, Hetty S, Salihovic S, Castillejo-Lopez C, Ganna A, Cook NL, Broeckling CD, Prenni JE, Shen X, Giedraitis V, Ärnlöv J, Lind L, Berne C, Sundström J, Fall T, Ingelsson E. Nowak C, et al. Sci Rep. 2018 Jun 6;8(1):8691. doi: 10.1038/s41598-018-26701-0. Sci Rep. 2018. PMID: 29875472 Free PMC article.

3

FKBP5 expression in human adipose tissue: potential role in glucose and lipid metabolism, adipogenesis and type 2 diabetes.

Sidibeh CO, Pereira MJ, Abalo XM, J Boersma G, Skrtic S, Lundkvist P, Katsogiannos P, Hausch F, Castillejo-López C, Eriksson JW. Sidibeh CO, et al. Endocrine. 2018 Oct;62(1):116-128. doi: 10.1007/s12020-018-1674-5. Epub 2018 Jul 21. Endocrine. 2018. PMID: 30032404 Free PMC article.

4

Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover.

Kamble PG, Pereira MJ, Gustafsson S, Lundkvist P, Castillejo-López C, Fall T, Ingelsson E, Eriksson JW. Kamble PG, et al. Adipocyte. 2018;7(4):285-296. doi: 10.1080/21623945.2018.1503030. Epub 2018 Aug 14. Adipocyte. 2018. PMID: 30064293 Free PMC article.

5

Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation.

Castillejo-Lopez C, Pjanic M, Pirona AC, Hetty S, Wabitsch M, Wadelius C, Quertermous T, Arner E, Ingelsson E. Castillejo-Lopez C, et al. iScience. 2019 Oct 25;20:42-59. doi: 10.1016/j.isci.2019.09.006. Epub 2019 Sep 10. iScience. 2019. PMID: 31557715 Free PMC article.

6

CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation.

Cook NL, Pjanic M, Emmerich AG, Rao AS, Hetty S, Knowles JW, Quertermous T, Castillejo-López C, Ingelsson E. Cook NL, et al. Among authors: castillejo lopez c. BMC Endocr Disord. 2019 Oct 29;19(1):115. doi: 10.1186/s12902-019-0442-8. BMC Endocr Disord. 2019. PMID: 31664995 Free PMC article.

7

Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues.

Diamanti K, Cavalli M, Pereira MJ, Pan G, Castillejo-López C, Kumar C, Mundt F, Komorowski J, Deshmukh AS, Mann M, Korsgren O, Eriksson JW, Wadelius C. Diamanti K, et al. Among authors: castillejo lopez c. Cell Rep Med. 2022 Oct 18;3(10):100763. doi: 10.1016/j.xcrm.2022.100763. Epub 2022 Oct 4. Cell Rep Med. 2022. PMID: 36198307 Free PMC article.

8

A regulatory element associated to NAFLD in the promoter of DIO1 controls LDL-C, HDL-C and triglycerides in hepatic cells.

Castillejo-López C, Bárcenas-Walls JR, Cavalli M, Larsson A, Wadelius C. Castillejo-López C, et al. Lipids Health Dis. 2024 Feb 16;23(1):48. doi: 10.1186/s12944-024-02029-9. Lipids Health Dis. 2024. PMID: 38365720 Free PMC article.

9

Deubiquitinating enzymes USP4 and USP17 finetune the trafficking of PDGFRβ and affect PDGF-BB-induced STAT3 signalling.

Sarri N, Wang K, Tsioumpekou M, Castillejo-López C, Lennartsson J, Heldin CH, Papadopoulos N. Sarri N, et al. Among authors: castillejo lopez c. Cell Mol Life Sci. 2022 Jan 21;79(2):85. doi: 10.1007/s00018-022-04128-1. Cell Mol Life Sci. 2022. PMID: 35064336 Free PMC article.

10

CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence.

Kolliopoulos C, Ali MM, Castillejo-Lopez C, Heldin CH, Heldin P. Kolliopoulos C, et al. Among authors: castillejo lopez c. Cancers (Basel). 2022 Jul 31;14(15):3747. doi: 10.3390/cancers14153747. Cancers (Basel). 2022. PMID: 35954411 Free PMC article.

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