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Page 1
Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents.
Riether C, Pabst T, Höpner S, Bacher U, Hinterbrandner M, Banz Y, Müller R, Manz MG, Gharib WH, Francisco D, Bruggmann R, van Rompaey L, Moshir M, Delahaye T, Gandini D, Erzeel E, Hultberg A, Fung S, de Haard H, Leupin N, Ochsenbein AF. Riether C, et al. Among authors: bruggmann r. Nat Med. 2020 Sep;26(9):1459-1467. doi: 10.1038/s41591-020-0910-8. Epub 2020 Jun 29. Nat Med. 2020. PMID: 32601337 Clinical Trial.
Cycles of fusion and fission enabled rapid parallel adaptive radiations in African cichlids.
Meier JI, McGee MD, Marques DA, Mwaiko S, Kishe M, Wandera S, Neumann D, Mrosso H, Chapman LJ, Chapman CA, Kaufman L, Taabu-Munyaho A, Wagner CE, Bruggmann R, Excoffier L, Seehausen O. Meier JI, et al. Among authors: bruggmann r. Science. 2023 Sep 29;381(6665):eade2833. doi: 10.1126/science.ade2833. Epub 2023 Sep 29. Science. 2023. PMID: 37769075
Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma.
Xu D, Liang SQ, Yang H, Lüthi U, Riether C, Berezowska S, Marti TM, Hall SRR, Bruggmann R, Kocher GJ, Schmid RA, Peng RW. Xu D, et al. Among authors: bruggmann r. Br J Cancer. 2018 Jul;119(1):65-75. doi: 10.1038/s41416-018-0145-3. Epub 2018 Jun 20. Br J Cancer. 2018. PMID: 29921948 Free PMC article.
Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549.
Tièche CC, Gao Y, Bührer ED, Hobi N, Berezowska SA, Wyler K, Froment L, Weis S, Peng RW, Bruggmann R, Schär P, Amrein MA, Hall SRR, Dorn P, Kocher G, Riether C, Ochsenbein A, Schmid RA, Marti TM. Tièche CC, et al. Among authors: bruggmann r. Neoplasia. 2019 Feb;21(2):185-196. doi: 10.1016/j.neo.2018.09.008. Epub 2018 Dec 27. Neoplasia. 2019. PMID: 30591423 Free PMC article.
Contribution of brain pericytes in blood-brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells.
Heymans M, Figueiredo R, Dehouck L, Francisco D, Sano Y, Shimizu F, Kanda T, Bruggmann R, Engelhardt B, Winter P, Gosselet F, Culot M. Heymans M, et al. Among authors: bruggmann r. Fluids Barriers CNS. 2020 Jul 28;17(1):48. doi: 10.1186/s12987-020-00208-1. Fluids Barriers CNS. 2020. PMID: 32723387 Free PMC article.
Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage.
Deng H, Gao Y, Trappetti V, Hertig D, Karatkevich D, Losmanova T, Urzi C, Ge H, Geest GA, Bruggmann R, Djonov V, Nuoffer JM, Vermathen P, Zamboni N, Riether C, Ochsenbein A, Peng RW, Kocher GJ, Schmid RA, Dorn P, Marti TM. Deng H, et al. Among authors: bruggmann r. Cell Mol Life Sci. 2022 Jul 25;79(8):445. doi: 10.1007/s00018-022-04453-5. Cell Mol Life Sci. 2022. PMID: 35877003 Free PMC article.
Claudin-3-deficient C57BL/6J mice display intact brain barriers.
Castro Dias M, Coisne C, Lazarevic I, Baden P, Hata M, Iwamoto N, Francisco DMF, Vanlandewijck M, He L, Baier FA, Stroka D, Bruggmann R, Lyck R, Enzmann G, Deutsch U, Betsholtz C, Furuse M, Tsukita S, Engelhardt B. Castro Dias M, et al. Among authors: bruggmann r. Sci Rep. 2019 Jan 18;9(1):203. doi: 10.1038/s41598-018-36731-3. Sci Rep. 2019. PMID: 30659216 Free PMC article.
Publisher Correction: Claudin-3-deficient C57BL/6J mice display intact brain barriers.
Dias MC, Coisne C, Lazarevic I, Baden P, Hata M, Iwamoto N, Francisco DMF, Vanlandewijck M, He L, Baier FA, Stroka D, Bruggmann R, Lyck R, Enzmann G, Deutsch U, Betsholtz C, Furuse M, Tsukita S, Engelhardt B. Dias MC, et al. Among authors: bruggmann r. Sci Rep. 2019 Jul 18;9(1):10702. doi: 10.1038/s41598-019-43511-0. Sci Rep. 2019. PMID: 31320665 Free PMC article.
Advancing brain barriers RNA sequencing: guidelines from experimental design to publication.
Francisco DMF, Marchetti L, Rodríguez-Lorenzo S, Frías-Anaya E, Figueiredo RM; BtRAIN Network; Winter P, Romero IA, de Vries HE, Engelhardt B, Bruggmann R. Francisco DMF, et al. Among authors: bruggmann r. Fluids Barriers CNS. 2020 Aug 18;17(1):51. doi: 10.1186/s12987-020-00207-2. Fluids Barriers CNS. 2020. PMID: 32811511 Free PMC article. Review.
136 results