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Genetic reduction of cilium length by targeting intraflagellar transport 88 protein impedes kidney and liver cyst formation in mouse models of autosomal polycystic kidney disease.
Shao L, El-Jouni W, Kong F, Ramesh J, Kumar RS, Shen X, Ren J, Devendra S, Dorschel A, Wu M, Barrera I, Tabari A, Hu K, Haque N, Yambayev I, Li S, Kumar A, Behera TR, McDonough G, Furuichi M, Xifaras M, Lu T, Alhayaza RM, Miyabayashi K, Fan Q, Ajay AK, Zhou J. Shao L, et al. Among authors: ajay ak. Kidney Int. 2020 Nov;98(5):1225-1241. doi: 10.1016/j.kint.2020.05.049. Epub 2020 Jun 28. Kidney Int. 2020. PMID: 32610050 Free article.
RNA Sequencing Identifies Novel Translational Biomarkers of Kidney Fibrosis.
Craciun FL, Bijol V, Ajay AK, Rao P, Kumar RK, Hutchinson J, Hofmann O, Joshi N, Luyendyk JP, Kusebauch U, Moss CL, Srivastava A, Himmelfarb J, Waikar SS, Moritz RL, Vaidya VS. Craciun FL, et al. Among authors: ajay ak. J Am Soc Nephrol. 2016 Jun;27(6):1702-13. doi: 10.1681/ASN.2015020225. Epub 2015 Oct 8. J Am Soc Nephrol. 2016. PMID: 26449608 Free PMC article.
Pharmacological and genetic depletion of fibrinogen protects from kidney fibrosis.
Craciun FL, Ajay AK, Hoffmann D, Saikumar J, Fabian SL, Bijol V, Humphreys BD, Vaidya VS. Craciun FL, et al. Among authors: ajay ak. Am J Physiol Renal Physiol. 2014 Aug 15;307(4):F471-84. doi: 10.1152/ajprenal.00189.2014. Epub 2014 Jul 9. Am J Physiol Renal Physiol. 2014. PMID: 25007874 Free PMC article.
KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease.
Mori Y, Ajay AK, Chang JH, Mou S, Zhao H, Kishi S, Li J, Brooks CR, Xiao S, Woo HM, Sabbisetti VS, Palmer SC, Galichon P, Li L, Henderson JM, Kuchroo VK, Hawkins J, Ichimura T, Bonventre JV. Mori Y, et al. Among authors: ajay ak. Cell Metab. 2021 May 4;33(5):1042-1061.e7. doi: 10.1016/j.cmet.2021.04.004. Cell Metab. 2021. PMID: 33951465 Free PMC article.
Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration.
Ajay AK, Zhao L, Vig S, Fujiwara M, Thakurela S, Jadhav S, Cho A, Chiu IJ, Ding Y, Ramachandran K, Mithal A, Bhatt A, Chaluvadi P, Gupta MK, Shah SI, Sabbisetti VS, Waaga-Gasser AM, Frank DA, Murugaiyan G, Bonventre JV, Hsiao LL. Ajay AK, et al. Cell Rep. 2022 Mar 8;38(10):110473. doi: 10.1016/j.celrep.2022.110473. Cell Rep. 2022. PMID: 35263586 Free PMC article.
56 results