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Page 1
Genetic reduction of cilium length by targeting intraflagellar transport 88 protein impedes kidney and liver cyst formation in mouse models of autosomal polycystic kidney disease.
Shao L, El-Jouni W, Kong F, Ramesh J, Kumar RS, Shen X, Ren J, Devendra S, Dorschel A, Wu M, Barrera I, Tabari A, Hu K, Haque N, Yambayev I, Li S, Kumar A, Behera TR, McDonough G, Furuichi M, Xifaras M, Lu T, Alhayaza RM, Miyabayashi K, Fan Q, Ajay AK, Zhou J. Shao L, et al. Among authors: barrera i. Kidney Int. 2020 Nov;98(5):1225-1241. doi: 10.1016/j.kint.2020.05.049. Epub 2020 Jun 28. Kidney Int. 2020. PMID: 32610050 Free article.
Gα12 is required for renal cystogenesis induced by Pkd1 inactivation.
Wu Y, Xu JX, El-Jouni W, Lu T, Li S, Wang Q, Tran M, Yu W, Wu M, Barrera IE, Bonventre JV, Zhou J, Denker BM, Kong T. Wu Y, et al. J Cell Sci. 2016 Oct 1;129(19):3675-3684. doi: 10.1242/jcs.190496. Epub 2016 Aug 5. J Cell Sci. 2016. PMID: 27505895 Free PMC article.
Craters on the melanoma surface facilitate tumor-immune interactions and demonstrate pathologic response to checkpoint blockade in humans.
Ludin A, Stirtz GL, Tal A, Nirmal AJ, Besson N, Jones SM, Pfaff KL, Manos M, Liu S, Barrera I, Gong Q, Rodrigues CP, Sahu A, Jerison E, Alessi JV, Ricciuti B, Richardson DS, Weiss JD, Moreau HM, Stanhope ME, Afeyan AB, Sefton J, McCall WD, Formato E, Yang S, Zhou Y, van Konijnenburg DPH, Cole HL, Cordova M, Deng L, Rajadhyaksha M, Quake SR, Awad MM, Chen F, Sorger PK, Hodi FS, Rodig SJ, Murphy GF, Zon LI. Ludin A, et al. Among authors: barrera i. bioRxiv [Preprint]. 2024 Sep 19:2024.09.18.613595. doi: 10.1101/2024.09.18.613595. bioRxiv. 2024. PMID: 39345527 Free PMC article. Preprint.
Plasmodium infection induces phenotypic, clonal, and spatial diversity among differentiating CD4+ T cells.
Williams CG, Moreira ML, Asatsuma T, Lee HJ, Li S, Burn TN, Barrera I, Murray E, Soon MSF, Engel JA, Khoury DS, Le S, Wanrooy BJ, Schienstock D, Alexandre YO, Skinner OP, Joseph R, Beattie L, Mueller SN, Chen F, Haque A. Williams CG, et al. Among authors: barrera i. Cell Rep. 2024 Sep 24;43(9):114754. doi: 10.1016/j.celrep.2024.114754. Epub 2024 Sep 6. Cell Rep. 2024. PMID: 39243375 Free article. No abstract available.
CD4+ T cells display a spectrum of recall dynamics during re-infection with malaria parasites.
Lee HJ, Moreira ML, Li S, Asatsuma T, Williams CG, Skinner OP, Asad S, Bramhall M, Jiang Z, Liu Z, Kerr AS, Engel JA, Soon MSF, Straube J, Barrera I, Murray E, Chen F, Nideffer J, Jagannathan P, Haque A. Lee HJ, et al. Among authors: barrera i. Nat Commun. 2024 Jun 28;15(1):5497. doi: 10.1038/s41467-024-49879-6. Nat Commun. 2024. PMID: 38944658 Free PMC article.
Plasmodium infection induces phenotypic, clonal, and spatial diversity among differentiating CD4+ T cells.
Williams CG, Moreira ML, Asatsuma T, Lee HJ, Li S, Barrera I, Murray E, Soon MSF, Engel JA, Khoury DS, Le S, Wanrooy BJ, Schienstock D, Alexandre YO, Skinner OP, Joseph R, Beattie L, Mueller SN, Chen F, Haque A. Williams CG, et al. Among authors: barrera i. Cell Rep. 2024 Jun 25;43(6):114317. doi: 10.1016/j.celrep.2024.114317. Epub 2024 Jun 5. Cell Rep. 2024. PMID: 38848213 Free article.
A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity.
Patel AG, Ashenberg O, Collins NB, Segerstolpe Å, Jiang S, Slyper M, Huang X, Caraccio C, Jin H, Sheppard H, Xu K, Chang TC, Orr BA, Shirinifard A, Chapple RH, Shen A, Clay MR, Tatevossian RG, Reilly C, Patel J, Lupo M, Cline C, Dionne D, Porter CBM, Waldman J, Bai Y, Zhu B, Barrera I, Murray E, Vigneau S, Napolitano S, Wakiro I, Wu J, Grimaldi G, Dellostritto L, Helvie K, Rotem A, Lako A, Cullen N, Pfaff KL, Karlström Å, Jané-Valbuena J, Todres E, Thorner A, Geeleher P, Rodig SJ, Zhou X, Stewart E, Johnson BE, Wu G, Chen F, Yu J, Goltsev Y, Nolan GP, Rozenblatt-Rosen O, Regev A, Dyer MA. Patel AG, et al. Among authors: barrera i. bioRxiv [Preprint]. 2024 Jan 16:2024.01.07.574538. doi: 10.1101/2024.01.07.574538. bioRxiv. 2024. PMID: 38260392 Free PMC article. Preprint.
Cortical somatostatin interneuron subtypes form cell-type-specific circuits.
Wu SJ, Sevier E, Dwivedi D, Saldi GA, Hairston A, Yu S, Abbott L, Choi DH, Sherer M, Qiu Y, Shinde A, Lenahan M, Rizzo D, Xu Q, Barrera I, Kumar V, Marrero G, Prönneke A, Huang S, Kullander K, Stafford DA, Macosko E, Chen F, Rudy B, Fishell G. Wu SJ, et al. Among authors: barrera i. Neuron. 2023 Sep 6;111(17):2675-2692.e9. doi: 10.1016/j.neuron.2023.05.032. Epub 2023 Jun 29. Neuron. 2023. PMID: 37390821 Free PMC article.
Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens.
Wang Y, Fan JL, Melms JC, Amin AD, Georgis Y, Barrera I, Ho P, Tagore S, Abril-Rodríguez G, He S, Jin Y, Biermann J, Hofree M, Caprio L, Berhe S, Khan SA, Henick BS, Ribas A, Macosko EZ, Chen F, Taylor AM, Schwartz GK, Carvajal RD, Azizi E, Izar B. Wang Y, et al. Among authors: barrera i. Nat Genet. 2023 Jan;55(1):19-25. doi: 10.1038/s41588-022-01268-9. Epub 2023 Jan 9. Nat Genet. 2023. PMID: 36624340 Free PMC article.
Dissecting the treatment-naive ecosystem of human melanoma brain metastasis.
Biermann J, Melms JC, Amin AD, Wang Y, Caprio LA, Karz A, Tagore S, Barrera I, Ibarra-Arellano MA, Andreatta M, Fullerton BT, Gretarsson KH, Sahu V, Mangipudy VS, Nguyen TTT, Nair A, Rogava M, Ho P, Koch PD, Banu M, Humala N, Mahajan A, Walsh ZH, Shah SB, Vaccaro DH, Caldwell B, Mu M, Wünnemann F, Chazotte M, Berhe S, Luoma AM, Driver J, Ingham M, Khan SA, Rapisuwon S, Slingluff CL Jr, Eigentler T, Röcken M, Carvajal R, Atkins MB, Davies MA, Agustinus A, Bakhoum SF, Azizi E, Siegelin M, Lu C, Carmona SJ, Hibshoosh H, Ribas A, Canoll P, Bruce JN, Bi WL, Agrawal P, Schapiro D, Hernando E, Macosko EZ, Chen F, Schwartz GK, Izar B. Biermann J, et al. Among authors: barrera i. Cell. 2022 Jul 7;185(14):2591-2608.e30. doi: 10.1016/j.cell.2022.06.007. Cell. 2022. PMID: 35803246 Free PMC article.
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