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TET2 coactivates gene expression through demethylation of enhancers.
Wang L, Ozark PA, Smith ER, Zhao Z, Marshall SA, Rendleman EJ, Piunti A, Ryan C, Whelan AL, Helmin KA, Morgan MA, Zou L, Singer BD, Shilatifard A. Wang L, et al. Among authors: marshall sa. Sci Adv. 2018 Nov 7;4(11):eaau6986. doi: 10.1126/sciadv.aau6986. eCollection 2018 Nov. Sci Adv. 2018. PMID: 30417100 Free PMC article.
Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.
Rickels R, Herz HM, Sze CC, Cao K, Morgan MA, Collings CK, Gause M, Takahashi YH, Wang L, Rendleman EJ, Marshall SA, Krueger A, Bartom ET, Piunti A, Smith ER, Abshiru NA, Kelleher NL, Dorsett D, Shilatifard A. Rickels R, et al. Among authors: marshall sa. Nat Genet. 2017 Nov;49(11):1647-1653. doi: 10.1038/ng.3965. Epub 2017 Oct 2. Nat Genet. 2017. PMID: 28967912 Free PMC article.
A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation.
Morgan MAJ, Rickels RA, Collings CK, He X, Cao K, Herz HM, Cozzolino KA, Abshiru NA, Marshall SA, Rendleman EJ, Sze CC, Piunti A, Kelleher NL, Savas JN, Shilatifard A. Morgan MAJ, et al. Among authors: marshall sa. Genes Dev. 2017 Oct 1;31(19):2003-2014. doi: 10.1101/gad.305201.117. Genes Dev. 2017. PMID: 29089422 Free PMC article.
Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.
Wang L, Zhao Z, Ozark PA, Fantini D, Marshall SA, Rendleman EJ, Cozzolino KA, Louis N, He X, Morgan MA, Takahashi YH, Collings CK, Smith ER, Ntziachristos P, Savas JN, Zou L, Hashizume R, Meeks JJ, Shilatifard A. Wang L, et al. Among authors: marshall sa. Nat Med. 2018 Jun;24(6):758-769. doi: 10.1038/s41591-018-0034-6. Epub 2018 May 21. Nat Med. 2018. PMID: 29785026 Free PMC article.
271 results