Smith LK - Search Results

1

Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain.

Horowitz AM, Fan X, Bieri G, Smith LK, Sanchez-Diaz CI, Schroer AB, Gontier G, Casaletto KB, Kramer JH, Williams KE, Villeda SA. Horowitz AM, et al. Among authors: smith lk. Science. 2020 Jul 10;369(6500):167-173. doi: 10.1126/science.aaw2622. Science. 2020. PMID: 32646997 Free PMC article.

2

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.

Villeda SA, Plambeck KE, Middeldorp J, Castellano JM, Mosher KI, Luo J, Smith LK, Bieri G, Lin K, Berdnik D, Wabl R, Udeochu J, Wheatley EG, Zou B, Simmons DA, Xie XS, Longo FM, Wyss-Coray T. Villeda SA, et al. Among authors: smith lk. Nat Med. 2014 Jun;20(6):659-63. doi: 10.1038/nm.3569. Epub 2014 May 4. Nat Med. 2014. PMID: 24793238 Free PMC article.

3

β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis.

Smith LK, He Y, Park JS, Bieri G, Snethlage CE, Lin K, Gontier G, Wabl R, Plambeck KE, Udeochu J, Wheatley EG, Bouchard J, Eggel A, Narasimha R, Grant JL, Luo J, Wyss-Coray T, Villeda SA. Smith LK, et al. Nat Med. 2015 Aug;21(8):932-7. doi: 10.1038/nm.3898. Epub 2015 Jul 6. Nat Med. 2015. PMID: 26147761 Free PMC article.

4

Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner.

Deczkowska A, Matcovitch-Natan O, Tsitsou-Kampeli A, Ben-Hamo S, Dvir-Szternfeld R, Spinrad A, Singer O, David E, Winter DR, Smith LK, Kertser A, Baruch K, Rosenzweig N, Terem A, Prinz M, Villeda S, Citri A, Amit I, Schwartz M. Deczkowska A, et al. Among authors: smith lk. Nat Commun. 2017 Sep 28;8(1):717. doi: 10.1038/s41467-017-00769-0. Nat Commun. 2017. PMID: 28959042 Free PMC article.

5

The systemic environment: at the interface of aging and adult neurogenesis.

Smith LK, White CW 3rd, Villeda SA. Smith LK, et al. Cell Tissue Res. 2018 Jan;371(1):105-113. doi: 10.1007/s00441-017-2715-8. Epub 2017 Nov 9. Cell Tissue Res. 2018. PMID: 29124393 Free PMC article. Review.

6

Tissue-Resident Group 2 Innate Lymphoid Cells Differentiate by Layered Ontogeny and In Situ Perinatal Priming.

Schneider C, Lee J, Koga S, Ricardo-Gonzalez RR, Nussbaum JC, Smith LK, Villeda SA, Liang HE, Locksley RM. Schneider C, et al. Among authors: smith lk. Immunity. 2019 Jun 18;50(6):1425-1438.e5. doi: 10.1016/j.immuni.2019.04.019. Epub 2019 May 22. Immunity. 2019. PMID: 31128962 Free PMC article.

7

Tolerance induction and microglial engraftment after fetal therapy without conditioning in mice with Mucopolysaccharidosis type VII.

Nguyen QH, Witt RG, Wang B, Eikani C, Shea J, Smith LK, Boyle G, Cadaoas J, Sper R, MacKenzie JD, Villeda S, MacKenzie TC. Nguyen QH, et al. Among authors: smith lk. Sci Transl Med. 2020 Feb 26;12(532):eaay8980. doi: 10.1126/scitranslmed.aay8980. Sci Transl Med. 2020. PMID: 32102934

8

The aged hematopoietic system promotes hippocampal-dependent cognitive decline.

Smith LK, Verovskaya E, Bieri G, Horowitz AM, von Ungern-Sternberg SNI, Lin K, Seizer P, Passegué E, Villeda SA. Smith LK, et al. Aging Cell. 2020 Aug;19(8):e13192. doi: 10.1111/acel.13192. Epub 2020 Jul 21. Aging Cell. 2020. PMID: 33073926 Free PMC article.

9

Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.

Ho TT, Dellorusso PV, Verovskaya EV, Bakker ST, Flach J, Smith LK, Ventura PB, Lansinger OM, Hérault A, Zhang SY, Kang YA, Mitchell CA, Villeda SA, Passegué E. Ho TT, et al. Among authors: smith lk. J Exp Med. 2021 Jul 5;218(7):e20210223. doi: 10.1084/jem.20210223. Epub 2021 May 25. J Exp Med. 2021. PMID: 34032859 Free PMC article.

10

MHC class I H2-Kb negatively regulates neural progenitor cell proliferation by inhibiting FGFR signaling.

Lin K, Bieri G, Gontier G, Müller S, Smith LK, Snethlage CE, White CW 3rd, Maybury-Lewis SY, Villeda SA. Lin K, et al. Among authors: smith lk. PLoS Biol. 2021 Jun 28;19(6):e3001311. doi: 10.1371/journal.pbio.3001311. eCollection 2021 Jun. PLoS Biol. 2021. PMID: 34181639 Free PMC article.

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