Deng X - Search Results

1

Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.

Li G, Wang Y, Li L, Ren Y, Deng X, Liu J, Wang W, Luo M, Liu S, Chen J. Li G, et al. Among authors: deng x. Eur J Med Chem. 2020 Sep 15;202:112519. doi: 10.1016/j.ejmech.2020.112519. Epub 2020 Jun 27. Eur J Med Chem. 2020. PMID: 32650183

2

Discovery of novel cell-penetrating and tumor-targeting peptide-drug conjugate (PDC) for programmable delivery of paclitaxel and cancer treatment.

Deng X, Mai R, Zhang C, Yu D, Ren Y, Li G, Cheng B, Li L, Yu Z, Chen J. Deng X, et al. Eur J Med Chem. 2021 Mar 5;213:113050. doi: 10.1016/j.ejmech.2020.113050. Epub 2020 Nov 27. Eur J Med Chem. 2021. PMID: 33280896

3

Design, Synthesis, and Bioevaluation of Novel Enzyme-Triggerable Cell Penetrating Peptide-Based Dendrimers for Targeted Delivery of Camptothecin and Cancer Therapy.

Mai R, Deng B, Zhao H, Li L, Fang Y, Li S, Deng X, Chen J. Mai R, et al. Among authors: deng x, deng b. J Med Chem. 2022 Apr 14;65(7):5850-5865. doi: 10.1021/acs.jmedchem.2c00287. Epub 2022 Apr 5. J Med Chem. 2022. PMID: 35380045

4

Synthesis and pharmacological evaluation of a novel synthetic peptide CWHTH based on the Styela clava-derived natural peptide LWHTH with improved antioxidant, hepatoprotective and angiotensin converting enzyme inhibitory activities.

Deng X, Mai R, Zhang C, Liu J, Ren Y, Li G, Chen J. Deng X, et al. Int J Pharm. 2021 Aug 10;605:120852. doi: 10.1016/j.ijpharm.2021.120852. Epub 2021 Jul 3. Int J Pharm. 2021. PMID: 34224842

5

Design, synthesis and biological evaluation of novel peptides with anti-cancer and drug resistance-reversing activities.

Deng X, Qiu Q, Yang B, Wang X, Huang W, Qian H. Deng X, et al. Eur J Med Chem. 2015 Jan 7;89:540-8. doi: 10.1016/j.ejmech.2014.10.072. Epub 2014 Oct 28. Eur J Med Chem. 2015. PMID: 25462264

6

Potent hydrazone derivatives targeting esophageal cancer cells.

Li LY, Peng JD, Zhou W, Qiao H, Deng X, Li ZH, Li JD, Fu YD, Li S, Sun K, Liu HM, Zhao W. Li LY, et al. Among authors: deng x. Eur J Med Chem. 2018 Mar 25;148:359-371. doi: 10.1016/j.ejmech.2018.02.033. Epub 2018 Feb 14. Eur J Med Chem. 2018. PMID: 29475156

7

Design, synthesis and biological evaluation of novel peptide MC62 analogues as potential antihyperglycemic agents.

Yang B, Mei Y, Wang X, Deng X, Qian H, Huang W. Yang B, et al. Among authors: deng x. Eur J Med Chem. 2014 Feb 12;73:105-11. doi: 10.1016/j.ejmech.2013.11.043. Epub 2013 Dec 12. Eur J Med Chem. 2014. PMID: 24384551

8

Design, Synthesis, and Pharmacological Characterization of N-(4-(2 (6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)yl)ethyl)phenyl)quinazolin-4-amine Derivatives: Novel Inhibitors Reversing P-Glycoprotein-Mediated Multidrug Resistance.

Qiu Q, Liu B, Cui J, Li Z, Deng X, Qiang H, Li J, Liao C, Zhang B, Shi W, Pan M, Huang W, Qian H. Qiu Q, et al. Among authors: deng x. J Med Chem. 2017 Apr 27;60(8):3289-3302. doi: 10.1021/acs.jmedchem.6b01787. Epub 2017 Apr 5. J Med Chem. 2017. PMID: 28355069

9

Double π-Extended Helicene Derivatives Containing Pentagonal Rings: Synthesis, Crystal Analyses, and Photophysics.

Wei L, Deng X, Yu X, Li X, Wang W, Zhang C, Xiao J. Wei L, et al. Among authors: deng x. J Org Chem. 2021 Dec 17;86(24):17535-17542. doi: 10.1021/acs.joc.1c00989. Epub 2021 Oct 13. J Org Chem. 2021. PMID: 34643389

10

Corrigendum to 'Design, synthesis and biological evaluation of novel peptides with anti-cancer and drug resistance-reversing activities'[European Journal of Medicinal Chemistry, 89 (2015) 540-548].

Deng X, Qiu Q, Yang B, Wang X, Huang W, Qian H. Deng X, et al. Eur J Med Chem. 2022 Feb 15;230:114107. doi: 10.1016/j.ejmech.2022.114107. Epub 2022 Jan 13. Eur J Med Chem. 2022. PMID: 35033826 No abstract available.

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