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Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein.
Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, MacRenaris KW, Jones T, Day S, Myers L, Eun-Hyung Lee F, Nguyen DC, Sanz I, Martinez DR, Rothlauf PW, Bloyet LM, Whelan SPJ, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr. Zost SJ, et al. Among authors: chen ec, chen re. Nat Med. 2020 Sep;26(9):1422-1427. doi: 10.1038/s41591-020-0998-x. Epub 2020 Jul 10. Nat Med. 2020. PMID: 32651581 Free PMC article.
Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals.
Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, Martinez DR, Schäfer A, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Zost SJ, et al. Among authors: chen ec, chen re. bioRxiv [Preprint]. 2020 May 22:2020.05.22.111005. doi: 10.1101/2020.05.22.111005. bioRxiv. 2020. Update in: Nature. 2020 Aug;584(7821):443-449. doi: 10.1038/s41586-020-2548-6 PMID: 32511409 Free PMC article. Updated. Preprint.
Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein.
Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, MacRenaris KW, Jones T, Day S, Myers L, Lee FE, Nguyen DC, Sanz I, Martinez DR, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Zost SJ, et al. Among authors: chen ec, chen re. bioRxiv [Preprint]. 2020 May 13:2020.05.12.091462. doi: 10.1101/2020.05.12.091462. bioRxiv. 2020. Update in: Nat Med. 2020 Sep;26(9):1422-1427. doi: 10.1038/s41591-020-0998-x PMID: 32511414 Free PMC article. Updated. Preprint.
High Frequency of Shared Clonotypes in Human T Cell Receptor Repertoires.
Soto C, Bombardi RG, Kozhevnikov M, Sinkovits RS, Chen EC, Branchizio A, Kose N, Day SB, Pilkinton M, Gujral M, Mallal S, Crowe JE Jr. Soto C, et al. Among authors: chen ec. Cell Rep. 2020 Jul 14;32(2):107882. doi: 10.1016/j.celrep.2020.107882. Cell Rep. 2020. PMID: 32668251 Free PMC article.
Potently neutralizing and protective human antibodies against SARS-CoV-2.
Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr. Zost SJ, et al. Among authors: chen ec, chen re. Nature. 2020 Aug;584(7821):443-449. doi: 10.1038/s41586-020-2548-6. Epub 2020 Jul 15. Nature. 2020. PMID: 32668443 Free PMC article.
Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein.
Suryadevara N, Shrihari S, Gilchuk P, VanBlargan LA, Binshtein E, Zost SJ, Nargi RS, Sutton RE, Winkler ES, Chen EC, Fouch ME, Davidson E, Doranz BJ, Carnahan RH, Thackray LB, Diamond MS, Crowe JE. Suryadevara N, et al. Among authors: chen ec. bioRxiv [Preprint]. 2021 Jan 20:2021.01.19.427324. doi: 10.1101/2021.01.19.427324. bioRxiv. 2021. Update in: Cell. 2021 Apr 29;184(9):2316-2331.e15. doi: 10.1016/j.cell.2021.03.029 PMID: 33501445 Free PMC article. Updated. Preprint.
Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail.
Dong J, Zost S, Greaney A, Starr TN, Dingens AS, Chen EC, Chen R, Case B, Sutton R, Gilchuk P, Rodriguez J, Armstrong E, Gainza C, Nargi R, Binshtein E, Xie X, Zhang X, Shi PY, Logue J, Weston S, McGrath M, Frieman M, Brady T, Tuffy K, Bright H, Loo YM, McvTamney P, Esser M, Carnahan R, Diamond M, Bloom J, Crowe JE. Dong J, et al. Among authors: chen ec, chen r. bioRxiv [Preprint]. 2021 Mar 1:2021.01.27.428529. doi: 10.1101/2021.01.27.428529. bioRxiv. 2021. Update in: Nat Microbiol. 2021 Oct;6(10):1233-1244. doi: 10.1038/s41564-021-00972-2 PMID: 33532768 Free PMC article. Updated. Preprint.
Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein.
Suryadevara N, Shrihari S, Gilchuk P, VanBlargan LA, Binshtein E, Zost SJ, Nargi RS, Sutton RE, Winkler ES, Chen EC, Fouch ME, Davidson E, Doranz BJ, Chen RE, Shi PY, Carnahan RH, Thackray LB, Diamond MS, Crowe JE Jr. Suryadevara N, et al. Among authors: chen ec, chen re. Cell. 2021 Apr 29;184(9):2316-2331.e15. doi: 10.1016/j.cell.2021.03.029. Epub 2021 Mar 16. Cell. 2021. PMID: 33773105 Free PMC article.
Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals.
Chen EC, Gilchuk P, Zost SJ, Suryadevara N, Winkler ES, Cabel CR, Binshtein E, Sutton RE, Rodriguez J, Day S, Myers L, Trivette A, Williams JK, Davidson E, Li S, Doranz BJ, Campos SK, Carnahan RH, Thorne CA, Diamond MS, Crowe JE. Chen EC, et al. bioRxiv [Preprint]. 2021 May 3:2021.05.02.442326. doi: 10.1101/2021.05.02.442326. bioRxiv. 2021. Update in: Cell Rep. 2021 Aug 24;36(8):109604. doi: 10.1016/j.celrep.2021.109604 PMID: 33972937 Free PMC article. Updated. Preprint.
222 results