Nguyen N - Search Results

1

Mitochondrial Damage and Biogenesis in Acetaminophen-induced Liver Injury.

Jaeschke H, Duan L, Nguyen N, Ramachandran A. Jaeschke H, et al. Among authors: nguyen n. Liver Res. 2019 Dec;3(3-4):150-156. doi: 10.1016/j.livres.2019.10.002. Epub 2019 Nov 1. Liver Res. 2019. PMID: 32655976 Free PMC article.

2

Aldehyde dehydrogenase-2 activation decreases acetaminophen hepatotoxicity by prevention of mitochondrial depolarization.

Wimborne HJ, Hu J, Takemoto K, Nguyen NT, Jaeschke H, Lemasters JJ, Zhong Z. Wimborne HJ, et al. Toxicol Appl Pharmacol. 2020 Jun 1;396:114982. doi: 10.1016/j.taap.2020.114982. Epub 2020 Mar 30. Toxicol Appl Pharmacol. 2020. PMID: 32240663 Free PMC article.

3

Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice.

Nguyen NT, Du K, Akakpo JY, Umbaugh DS, Jaeschke H, Ramachandran A. Nguyen NT, et al. Toxicol Lett. 2021 Mar 1;338:21-31. doi: 10.1016/j.toxlet.2020.12.005. Epub 2020 Dec 5. Toxicol Lett. 2021. PMID: 33290831 Free PMC article.

4

Mitochondrial Membrane Potential Drives Early Change in Mitochondrial Morphology After Acetaminophen Exposure.

Umbaugh DS, Nguyen NT, Jaeschke H, Ramachandran A. Umbaugh DS, et al. Toxicol Sci. 2021 Feb 26;180(1):186-195. doi: 10.1093/toxsci/kfaa188. Toxicol Sci. 2021. PMID: 33432343 Free PMC article.

5

Impaired protein adduct removal following repeat administration of subtoxic doses of acetaminophen enhances liver injury in fed mice.

Nguyen NT, Akakpo JY, Weemhoff JL, Ramachandran A, Ding WX, Jaeschke H. Nguyen NT, et al. Arch Toxicol. 2021 Apr;95(4):1463-1473. doi: 10.1007/s00204-021-02985-6. Epub 2021 Jan 17. Arch Toxicol. 2021. PMID: 33458793 Free PMC article.

6

Kupffer cells regulate liver recovery through induction of chemokine receptor CXCR2 on hepatocytes after acetaminophen overdose in mice.

Nguyen NT, Umbaugh DS, Sanchez-Guerrero G, Ramachandran A, Jaeschke H. Nguyen NT, et al. Arch Toxicol. 2022 Jan;96(1):305-320. doi: 10.1007/s00204-021-03183-0. Epub 2021 Nov 1. Arch Toxicol. 2022. PMID: 34724096 Free PMC article.

7

Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and how to avoid common pitfalls.

Jaeschke H, Adelusi OB, Akakpo JY, Nguyen NT, Sanchez-Guerrero G, Umbaugh DS, Ding WX, Ramachandran A. Jaeschke H, et al. Acta Pharm Sin B. 2021 Dec;11(12):3740-3755. doi: 10.1016/j.apsb.2021.09.023. Epub 2021 Sep 30. Acta Pharm Sin B. 2021. PMID: 35024303 Free PMC article. Review.

8

Recovered Hepatocytes Promote Macrophage Apoptosis Through CXCR4 After Acetaminophen-Induced Liver Injury in Mice.

Nguyen NT, Umbaugh DS, Huang EL, Adelusi OB, Sanchez Guerrero G, Ramachandran A, Jaeschke H. Nguyen NT, et al. Toxicol Sci. 2022 Jul 28;188(2):248-260. doi: 10.1093/toxsci/kfac057. Toxicol Sci. 2022. PMID: 35642939 Free PMC article.

9

Platanosides, a Potential Botanical Drug Combination, Decrease Liver Injury Caused by Acetaminophen Overdose in Mice.

Samuvel DJ, Nguyen NT, Jaeschke H, Lemasters JJ, Wang X, Choo YM, Hamann MT, Zhong Z. Samuvel DJ, et al. J Nat Prod. 2022 Jul 22;85(7):1779-1788. doi: 10.1021/acs.jnatprod.2c00324. Epub 2022 Jul 10. J Nat Prod. 2022. PMID: 35815804 Free PMC article. Review.

10

Generation of pro-and anti-inflammatory mediators after acetaminophen overdose in surviving and non-surviving patients.

Woolbright BL, Nguyen NT, McGill MR, Sharpe MR, Curry SC, Jaeschke H. Woolbright BL, et al. Toxicol Lett. 2022 Aug 15;367:59-66. doi: 10.1016/j.toxlet.2022.07.813. Epub 2022 Jul 26. Toxicol Lett. 2022. PMID: 35905941 Free PMC article.

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