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Relationship between Gepotidacin Exposure and Prevention of On-Therapy Resistance Amplification in a Neisseria gonorrhoeae Hollow-Fiber In Vitro Infection Model.
VanScoy BD, Scangarella-Oman NE, Fikes S, Min S, Huang J, Ingraham K, Bhavnani SM, Conde H, Ambrose PG. VanScoy BD, et al. Among authors: fikes s. Antimicrob Agents Chemother. 2020 Sep 21;64(10):e00521-20. doi: 10.1128/AAC.00521-20. Print 2020 Sep 21. Antimicrob Agents Chemother. 2020. PMID: 32661002 Free PMC article.
Gepotidacin Pharmacokinetics-Pharmacodynamics against Escherichia coli in the One-Compartment and Hollow-Fiber In Vitro Infection Model Systems.
VanScoy BD, Lakota EA, Conde H, Fikes S, Bhavnani SM, Elefante PB, Scangarella-Oman NE, Ambrose PG. VanScoy BD, et al. Among authors: fikes s. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0012221. doi: 10.1128/AAC.00122-21. Epub 2021 Sep 20. Antimicrob Agents Chemother. 2021. PMID: 34543096 Free PMC article.
Use of an in vitro pharmacodynamic model to derive a moxifloxacin regimen that optimizes kill of Yersinia pestis and prevents emergence of resistance.
Louie A, Heine HS, VanScoy B, Eichas A, Files K, Fikes S, Brown DL, Liu W, Kinzig-Schippers M, Sörgel F, Drusano GL. Louie A, et al. Among authors: fikes s. Antimicrob Agents Chemother. 2011 Feb;55(2):822-30. doi: 10.1128/AAC.00818-10. Epub 2010 Nov 29. Antimicrob Agents Chemother. 2011. PMID: 21115791 Free PMC article.
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