Cox RM - Search Results

1

Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase.

Cox RM, Sourimant J, Toots M, Yoon JJ, Ikegame S, Govindarajan M, Watkinson RE, Thibault P, Makhsous N, Lin MJ, Marengo JR, Sticher Z, Kolykhalov AA, Natchus MG, Greninger AL, Lee B, Plemper RK. Cox RM, et al. Nat Microbiol. 2020 Oct;5(10):1232-1246. doi: 10.1038/s41564-020-0752-7. Epub 2020 Jul 13. Nat Microbiol. 2020. PMID: 32661315 Free PMC article.

2

Blocking Respiratory Syncytial Virus Entry: A Story with Twists.

Weisshaar M, Cox R, Plemper RK. Weisshaar M, et al. DNA Cell Biol. 2015 Aug;34(8):505-10. doi: 10.1089/dna.2015.2896. Epub 2015 May 11. DNA Cell Biol. 2015. PMID: 25961744 Free PMC article.

3

The paramyxovirus polymerase complex as a target for next-generation anti-paramyxovirus therapeutics.

Cox R, Plemper RK. Cox R, et al. Front Microbiol. 2015 May 12;6:459. doi: 10.3389/fmicb.2015.00459. eCollection 2015. Front Microbiol. 2015. PMID: 26029193 Free PMC article. Review.

4

Structure-guided design of small-molecule therapeutics against RSV disease.

Cox R, Plemper RK. Cox R, et al. Expert Opin Drug Discov. 2016;11(6):543-556. doi: 10.1517/17460441.2016.1174212. Epub 2016 Apr 21. Expert Opin Drug Discov. 2016. PMID: 27046051 Free PMC article.

5

Identification and Characterization of Influenza Virus Entry Inhibitors through Dual Myxovirus High-Throughput Screening.

Weisshaar M, Cox R, Morehouse Z, Kyasa SK, Yan D, Oberacker P, Mao S, Golden JE, Lowen AC, Natchus MG, Plemper RK. Weisshaar M, et al. J Virol. 2016 Jul 27;90(16):7368-7387. doi: 10.1128/JVI.00898-16. Print 2016 Aug 15. J Virol. 2016. PMID: 27252534 Free PMC article.

6

Releasing the Genomic RNA Sequestered in the Mumps Virus Nucleocapsid.

Severin C, Terrell JR, Zengel JR, Cox R, Plemper RK, He B, Luo M. Severin C, et al. J Virol. 2016 Oct 28;90(22):10113-10119. doi: 10.1128/JVI.01422-16. Print 2016 Nov 15. J Virol. 2016. PMID: 27581981 Free PMC article.

7

The structurally disordered paramyxovirus nucleocapsid protein tail domain is a regulator of the mRNA transcription gradient.

Cox RM, Krumm SA, Thakkar VD, Sohn M, Plemper RK. Cox RM, et al. Sci Adv. 2017 Feb 3;3(2):e1602350. doi: 10.1126/sciadv.1602350. eCollection 2017 Feb. Sci Adv. 2017. PMID: 28168220 Free PMC article.

8

Identification of Non-Nucleoside Inhibitors of the Respiratory Syncytial Virus Polymerase Complex.

Jiménez-Somarribas A, Mao S, Yoon JJ, Weisshaar M, Cox RM, Marengo JR, Mitchell DG, Morehouse ZP, Yan D, Solis I, Liotta DC, Natchus MG, Plemper RK. Jiménez-Somarribas A, et al. Among authors: cox rm. J Med Chem. 2017 Mar 23;60(6):2305-2325. doi: 10.1021/acs.jmedchem.6b01568. Epub 2017 Mar 13. J Med Chem. 2017. PMID: 28245119 Free PMC article.

9

Structure and organization of paramyxovirus particles.

Cox RM, Plemper RK. Cox RM, et al. Curr Opin Virol. 2017 Jun;24:105-114. doi: 10.1016/j.coviro.2017.05.004. Epub 2017 Jun 8. Curr Opin Virol. 2017. PMID: 28601688 Free PMC article. Review.

10

The Unstructured Paramyxovirus Nucleocapsid Protein Tail Domain Modulates Viral Pathogenesis through Regulation of Transcriptase Activity.

Thakkar VD, Cox RM, Sawatsky B, da Fontoura Budaszewski R, Sourimant J, Wabbel K, Makhsous N, Greninger AL, von Messling V, Plemper RK. Thakkar VD, et al. Among authors: cox rm. J Virol. 2018 Mar 28;92(8):e02064-17. doi: 10.1128/JVI.02064-17. Print 2018 Apr 15. J Virol. 2018. PMID: 29437959 Free PMC article.

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