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High-content, label-free analysis of proplatelet production from megakaryocytes.
French SL, Vijey P, Karhohs KW, Wilkie AR, Horin LJ, Ray A, Posorske B, Carpenter AE, Machlus KR, Italiano JE Jr. French SL, et al. Among authors: posorske b. J Thromb Haemost. 2020 Oct;18(10):2701-2711. doi: 10.1111/jth.15012. Epub 2020 Aug 23. J Thromb Haemost. 2020. PMID: 32662223 Free PMC article.
The small MAF transcription factor MAFG co-opts MITF to promote melanoma progression.
Vera O, Martinez M, Soto-Vargas Z, Wang K, Xu X, Ruiz-Buceta S, Mecozzi N, Chadourne M, Posorske B, Angarita A, Bok I, Liu Q, Murikipudi H, Kim Y, Messina JL, Tsai KY, Major MB, Lau EK, Yu X, Ibanez-de-Caceres I, Karreth FA. Vera O, et al. Among authors: posorske b. bioRxiv [Preprint]. 2024 Sep 6:2024.09.03.611024. doi: 10.1101/2024.09.03.611024. bioRxiv. 2024. PMID: 39282450 Free PMC article. Preprint.
MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability.
Jasani N, Xu X, Posorske B, Kim Y, Vera O, Tsai KY, DeNicola GM, Karreth FA. Jasani N, et al. Among authors: posorske b. bioRxiv [Preprint]. 2024 Apr 15:2024.04.11.589139. doi: 10.1101/2024.04.11.589139. bioRxiv. 2024. Update in: Cancer Res. 2025 Jan 15;85(2):314-328. doi: 10.1158/0008-5472.CAN-24-2471 PMID: 38659816 Free PMC article. Updated. Preprint.