Mian MY - Search Results

1

The α2,3-selective potentiators of GABA_A receptors, KRM-II-81 and MP-III-80, produce anxiolytic-like effects and block chemotherapy-induced hyperalgesia in mice without tolerance development.

Biggerstaff A, Kivell B, Smith JL, Mian MY, Golani LK, Rashid F, Sharmin D, Knutson DE, Cerne R, Cook JM, Witkin JM. Biggerstaff A, et al. Among authors: mian my. Pharmacol Biochem Behav. 2020 Sep;196:172996. doi: 10.1016/j.pbb.2020.172996. Epub 2020 Jul 12. Pharmacol Biochem Behav. 2020. PMID: 32668266

2

Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni.

McCusker P, Mian MY, Li G, Olp MD, Tiruveedhula VVNPB, Rashid F, Golani LK, Verma RS, Smith BC, Cook JM, Chan JD. McCusker P, et al. Among authors: mian my. PLoS Negl Trop Dis. 2019 Nov 15;13(11):e0007826. doi: 10.1371/journal.pntd.0007826. eCollection 2019 Nov. PLoS Negl Trop Dis. 2019. PMID: 31730614 Free PMC article.

3

The Effects of pH on the Structure and Bioavailability of Imidazobenzodiazepine-3-Carboxylate MIDD0301.

Roni MSR, Li G, Mikulsky BN, Knutson DE, Mian MY, Zahn NM, Cook JM, Stafford DC, Arnold LA. Roni MSR, et al. Among authors: mian my. Mol Pharm. 2020 Apr 6;17(4):1182-1192. doi: 10.1021/acs.molpharmaceut.9b01210. Epub 2020 Feb 26. Mol Pharm. 2020. PMID: 32069056 Free PMC article.

4

Targeting Nitric Oxide Production in Microglia with Novel Imidazodiazepines for Nonsedative Pain Treatment.

Nieman AN, Li G, Zahn NM, Mian MY, Mikulsky BN, Hoffman DA, Wilcox TM, Kehoe AS, Luecke IW, Poe MM, Alvarez-Carbonell D, Cook JM, Stafford DC, Arnold LA. Nieman AN, et al. Among authors: mian my. ACS Chem Neurosci. 2020 Jul 1;11(13):2019-2030. doi: 10.1021/acschemneuro.0c00324. Epub 2020 Jun 18. ACS Chem Neurosci. 2020. PMID: 32511908 Free PMC article.

5

Imidazodiazepine Anticonvulsant, KRM-II-81, Produces Novel, Non-diazepam-like Antiseizure Effects.

Knutson DE, Smith JL, Ping X, Jin X, Golani LK, Li G, Tiruveedhula VVNPB, Rashid F, Mian MY, Jahan R, Sharmin D, Cerne R, Cook JM, Witkin JM. Knutson DE, et al. Among authors: mian my. ACS Chem Neurosci. 2020 Sep 2;11(17):2624-2637. doi: 10.1021/acschemneuro.0c00295. Epub 2020 Aug 18. ACS Chem Neurosci. 2020. PMID: 32786313

6

A Structure-Activity Relationship Comparison of Imidazodiazepines Binding at Kappa, Mu, and Delta Opioid Receptors and the GABA_A Receptor.

Li G, Nieman AN, Mian MY, Zahn NM, Mikulsky BN, Poe MM, Methuku KR, Liu Y, Cook JM, Stafford DC, Arnold LA. Li G, et al. Among authors: mian my. Molecules. 2020 Aug 25;25(17):3864. doi: 10.3390/molecules25173864. Molecules. 2020. PMID: 32854311 Free PMC article.

7

Nebulized MIDD0301 Reduces Airway Hyperresponsiveness in Moderate and Severe Murine Asthma Models.

Zahn NM, Mikulsky BN, Roni MSR, Yocum GT, Mian MY, Knutson DE, Cook JM, Emala CW, Stafford DC, Arnold LA. Zahn NM, et al. Among authors: mian my. ACS Pharmacol Transl Sci. 2020 Dec 2;3(6):1381-1390. doi: 10.1021/acsptsci.0c00180. eCollection 2020 Dec 11. ACS Pharmacol Transl Sci. 2020. PMID: 33344908 Free PMC article.

8

Vasodilatory effects of a variety of positive allosteric modulators of GABA_A receptors on rat thoracic aorta.

Bojić MG, Todorović L, Santrač A, Mian MY, Sharmin D, Cook JM, Savić MM. Bojić MG, et al. Among authors: mian my. Eur J Pharmacol. 2021 May 15;899:174023. doi: 10.1016/j.ejphar.2021.174023. Epub 2021 Mar 13. Eur J Pharmacol. 2021. PMID: 33722589

9

Identification and Quantification of MIDD0301 Metabolites.

Roni MSR, Zahn NM, Mikulsky BN, Webb DA, Mian MY, Knutson DE, Guthrie ML, Cook JM, Stafford DC, Arnold LA. Roni MSR, et al. Among authors: mian my. Curr Drug Metab. 2021;22(14):1114-1123. doi: 10.2174/1389200222666211202093841. Curr Drug Metab. 2021. PMID: 34856893 Free PMC article.

10

The imidazodiazepine, KRM-II-81: An example of a newly emerging generation of GABAkines for neurological and psychiatric disorders.

Witkin JM, Lippa A, Smith JL, Jin X, Ping X, Biggerstaff A, Kivell BM, Knutson DE, Sharmin D, Pandey KP, Mian MY, Cook JM, Cerne R. Witkin JM, et al. Among authors: mian my. Pharmacol Biochem Behav. 2022 Feb;213:173321. doi: 10.1016/j.pbb.2021.173321. Epub 2022 Jan 15. Pharmacol Biochem Behav. 2022. PMID: 35041859 Review.

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