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Page 1
Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion.
Tovy A, Reyes JM, Gundry MC, Brunetti L, Lee-Six H, Petljak M, Park HJ, Guzman AG, Rosas C, Jeffries AR, Baple E, Mill J, Crosby AH, Sency V, Xin B, Machado HE, Castillo D, Weitzel JN, Li W, Stratton MR, Campbell PJ, Wang H, Sanders MA, Goodell MA. Tovy A, et al. Among authors: rosas c. Cell Stem Cell. 2020 Aug 6;27(2):326-335.e4. doi: 10.1016/j.stem.2020.06.018. Epub 2020 Jul 15. Cell Stem Cell. 2020. PMID: 32673568 Free PMC article.
Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome.
Tovy A, Rosas C, Gaikwad AS, Medrano G, Zhang L, Reyes JM, Huang YH, Arakawa T, Kurtz K, Conneely SE, Guzman AG, Aguilar R, Gao A, Chen CW, Kim JJ, Carter MT, Lasa-Aranzasti A, Valenzuela I, Van Maldergem L, Brunetti L, Hicks MJ, Marcogliese AN, Goodell MA, Rau RE. Tovy A, et al. Among authors: rosas c. Haematologica. 2022 Apr 1;107(4):887-898. doi: 10.3324/haematol.2021.278990. Haematologica. 2022. PMID: 34092059 Free PMC article.
Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis.
Tovy A, Reyes JM, Zhang L, Huang YH, Rosas C, Daquinag AC, Guzman A, Ramabadran R, Chen CW, Gu T, Gupta S, Ortinau L, Park D, Cox AR, Rau RE, Hartig SM, Kolonin MG, Goodell MA. Tovy A, et al. Among authors: rosas c. Elife. 2022 May 30;11:e72359. doi: 10.7554/eLife.72359. Elife. 2022. PMID: 35635747 Free PMC article.
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells.
Ramabadran R, Wang JH, Reyes JM, Guzman AG, Gupta S, Rosas C, Brunetti L, Gundry MC, Tovy A, Long H, Gu T, Cullen SM, Tyagi S, Rux D, Kim JJ, Kornblau SM, Kyba M, Stossi F, Rau RE, Takahashi K, Westbrook TF, Goodell MA. Ramabadran R, et al. Among authors: rosas c. Nat Cell Biol. 2023 Apr;25(4):528-539. doi: 10.1038/s41556-023-01109-9. Epub 2023 Apr 6. Nat Cell Biol. 2023. PMID: 37024683 Free PMC article.
TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells.
Hong T, Li J, Guo L, Cavalier M, Wang T, Dou Y, DeLaFuente A, Fang S, Guzman A, Wohlan K, Kapadia C, Rosas C, Yang Y, Yin CC, Li S, You MJ, Cheng X, Goodell MA, Zhou Y, Huang Y. Hong T, et al. Among authors: rosas c. Nat Aging. 2023 Nov;3(11):1387-1400. doi: 10.1038/s43587-023-00505-y. Epub 2023 Oct 26. Nat Aging. 2023. PMID: 37884767 Free PMC article.
Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation.
Reyes JM, Tovy A, Zhang L, Bortoletto AS, Rosas C, Chen CW, Waldvogel SM, Guzman AG, Aguilar R, Gupta S, Liu L, Buckley MT, Patel KR, Marcogliese AN, Li Y, Curry CV, Rando TA, Brunet A, Parchem RJ, Rau RE, Goodell MA. Reyes JM, et al. Among authors: rosas c. iScience. 2024 Feb 5;27(3):109122. doi: 10.1016/j.isci.2024.109122. eCollection 2024 Mar 15. iScience. 2024. PMID: 38414863 Free PMC article.
Erratum: Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation.
Reyes JM, Tovy A, Zhang L, Bortoletto AS, Rosas C, Chen CW, Waldvogel SM, Guzman AG, Aguilar R, Gupta S, Liu L, Buckley MT, Patel KR, Marcogliese AN, Li Y, Curry CV, Rando TA, Brunet A, Parchem RJ, Rau RE, Goodell MA. Reyes JM, et al. Among authors: rosas c. iScience. 2024 Jun 24;27(7):110313. doi: 10.1016/j.isci.2024.110313. eCollection 2024 Jul 19. iScience. 2024. PMID: 39027369 Free PMC article.
Ileal Predominance in Crohn's Disease Is Associated With Increased Intestinal Surgery and Biological Therapy Use, With Lower Treatment Persistence.
Giordano A, Pérez-Martínez I, Gisbert JP, Ricart E, Martín-Arranz MD, Mesonero F, De Castro Parga ML, Rivero M, Iglesias E, Fernández-Prada S, Calafat M, Arroyo Villarino MT, Ángel de Jorge Turrión M, Hernandez-Camba A, Lidón RV, Carpio D, Brunet E, Moranta FR, García LA, Cuquerella JT, Bermejo F, Madero L, Esteve M, González-Muñoza C, Martínez-Montiel P, Huguet JM, Pérez Calle JL, Rodríguez-Lago I, Ausín MS, Lorente Poyatos RH, García-Bosch O, Marín GS, Taxonera C, Ponferrada-Diaz Á, Acosta MB, Bujanda L, Serra RB, Ramos L, Vera I, Abizanda ES, Piqueras M, Gómez CS, García-Sepulcre MF, Arregui MV, Murillo NR, LLaó J, Lucendo AJ, Marín-Jiménez I, Camps-Aler B, Villafranca CM, Ceballos D, Ver Y, Fernández-Salazar LI, Alcaín G, Valldosera G, Andrés PR, Martínez-Flores C, Coronel AF, Ginard D, García L, Gómez IB, Argüelles-Arias F, Miyashiro EI, De la Piscina PR, Villalba LH, Notari PA, de Jesús Martínez-Pérez T, Fernández H, Gilabert P, Rosas CM, Nos P, Gil JL, Navas López VM, Muñoz F, Diz-Lois Palomares MT, Lucio AS, Merino O, Nicolás de Prado I, Leal C, Martín de Carpi J, Sánchez LB, Arce NM, Frago S, Mateu BB, Domènech E, Planella EG; ENEIDA project of GETECCU. Giordano A, et al. Among authors: rosas cm. Am J Gastroenterol. 2025 Jan 1;120(1):194-203. doi: 10.14309/ajg.0000000000003207. Epub 2024 Nov 14. Am J Gastroenterol. 2025. PMID: 39745305
168 results