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Page 1
Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.
Alencar GF, Owsiany KM, Karnewar S, Sukhavasi K, Mocci G, Nguyen AT, Williams CM, Shamsuzzaman S, Mokry M, Henderson CA, Haskins R, Baylis RA, Finn AV, McNamara CA, Zunder ER, Venkata V, Pasterkamp G, Björkegren J, Bekiranov S, Owens GK. Alencar GF, et al. Among authors: owsiany km. Circulation. 2020 Nov 24;142(21):2045-2059. doi: 10.1161/CIRCULATIONAHA.120.046672. Epub 2020 Jul 17. Circulation. 2020. PMID: 32674599 Free PMC article.
Multiple cell types contribute to the atherosclerotic lesion fibrous cap by PDGFRβ and bioenergetic mechanisms.
Newman AAC, Serbulea V, Baylis RA, Shankman LS, Bradley X, Alencar GF, Owsiany K, Deaton RA, Karnewar S, Shamsuzzaman S, Salamon A, Reddy MS, Guo L, Finn A, Virmani R, Cherepanova OA, Owens GK. Newman AAC, et al. Nat Metab. 2021 Feb;3(2):166-181. doi: 10.1038/s42255-020-00338-8. Epub 2021 Feb 22. Nat Metab. 2021. PMID: 33619382 Free PMC article.
Revealing the Origins of Foam Cells in Atherosclerotic Lesions.
Owsiany KM, Alencar GF, Owens GK. Owsiany KM, et al. Arterioscler Thromb Vasc Biol. 2019 May;39(5):836-838. doi: 10.1161/ATVBAHA.119.312557. Arterioscler Thromb Vasc Biol. 2019. PMID: 31017823 Free PMC article. No abstract available.
KLF4 (Kruppel-Like Factor 4)-Dependent Perivascular Plasticity Contributes to Adipose Tissue inflammation.
Bulut GB, Alencar GF, Owsiany KM, Nguyen AT, Karnewar S, Haskins RM, Waller LK, Cherepanova OA, Deaton RA, Shankman LS, Keller SR, Owens GK. Bulut GB, et al. Among authors: owsiany km. Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):284-301. doi: 10.1161/ATVBAHA.120.314703. Epub 2020 Oct 15. Arterioscler Thromb Vasc Biol. 2021. PMID: 33054397 Free PMC article.
SMC-Derived Hyaluronan Modulates Vascular SMC Phenotype in Murine Atherosclerosis.
Hartmann F, Gorski DJ, Newman AAC, Homann S, Petz A, Owsiany KM, Serbulea V, Zhou YQ, Deaton RA, Bendeck M, Owens GK, Fischer JW. Hartmann F, et al. Among authors: owsiany km. Circ Res. 2021 Nov 12;129(11):992-1005. doi: 10.1161/CIRCRESAHA.120.318479. Epub 2021 Oct 7. Circ Res. 2021. PMID: 34615369 Free PMC article.
Enhanced single-cell RNA-seq workflow reveals coronary artery disease cellular cross-talk and candidate drug targets.
Ma WF, Hodonsky CJ, Turner AW, Wong D, Song Y, Mosquera JV, Ligay AV, Slenders L, Gancayco C, Pan H, Barrientos NB, Mai D, Alencar GF, Owsiany K, Owens GK, Reilly MP, Li M, Pasterkamp G, Mokry M, van der Laan SW, Khomtchouk BB, Miller CL. Ma WF, et al. Atherosclerosis. 2022 Jan;340:12-22. doi: 10.1016/j.atherosclerosis.2021.11.025. Epub 2021 Nov 26. Atherosclerosis. 2022. PMID: 34871816 Free PMC article.