Li X - Search Results

1

Inhibition of IRAK4 kinase activity improves ethanol-induced liver injury in mice.

Wang H, Zhou H, Zhang Q, Poulsen KL, Taylor V, McMullen MR, Czarnecki D, Dasarathy D, Yu M, Liao Y, Allende DS, Chen X, Hong L, Zhao J, Yang J, Nagy LE, Li X. Wang H, et al. Among authors: li x. J Hepatol. 2020 Dec;73(6):1470-1481. doi: 10.1016/j.jhep.2020.07.016. Epub 2020 Jul 16. J Hepatol. 2020. PMID: 32682051 Free PMC article.

2

Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex.

Jiang Z, Johnson HJ, Nie H, Qin J, Bird TA, Li X. Jiang Z, et al. Among authors: li x. J Biol Chem. 2003 Mar 28;278(13):10952-6. doi: 10.1074/jbc.M212112200. Epub 2002 Dec 20. J Biol Chem. 2003. PMID: 12496252 Free article.

3

IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness.

Qin J, Jiang Z, Qian Y, Casanova JL, Li X. Qin J, et al. Among authors: li x. J Biol Chem. 2004 Jun 18;279(25):26748-53. doi: 10.1074/jbc.M400785200. Epub 2004 Apr 14. J Biol Chem. 2004. PMID: 15084582 Free article.

4

A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity.

Kim TW, Staschke K, Bulek K, Yao J, Peters K, Oh KH, Vandenburg Y, Xiao H, Qian W, Hamilton T, Min B, Sen G, Gilmour R, Li X. Kim TW, et al. Among authors: li x. J Exp Med. 2007 May 14;204(5):1025-36. doi: 10.1084/jem.20061825. Epub 2007 Apr 30. J Exp Med. 2007. PMID: 17470642 Free PMC article.

5

IRAK4 in TLR/IL-1R signaling: possible clinical applications.

Li X. Li X. Eur J Immunol. 2008 Mar;38(3):614-8. doi: 10.1002/eji.200838161. Eur J Immunol. 2008. PMID: 18286571 Free article.

6

The kinase activity of IL-1 receptor-associated kinase 4 is required for interleukin-1 receptor/toll-like receptor-induced TAK1-dependent NFkappaB activation.

Fraczek J, Kim TW, Xiao H, Yao J, Wen Q, Li Y, Casanova JL, Pryjma J, Li X. Fraczek J, et al. Among authors: li y, li x. J Biol Chem. 2008 Nov 14;283(46):31697-705. doi: 10.1074/jbc.M804779200. Epub 2008 Sep 15. J Biol Chem. 2008. PMID: 18794297 Free PMC article.

7

The dual functions of IL-1 receptor-associated kinase 2 in TLR9-mediated IFN and proinflammatory cytokine production.

Wan Y, Kim TW, Yu M, Zhou H, Yamashita M, Kang Z, Yin W, Wang JA, Thomas J, Sen GC, Stark GR, Li X. Wan Y, et al. Among authors: li x. J Immunol. 2011 Mar 1;186(5):3006-14. doi: 10.4049/jimmunol.1003217. Epub 2011 Jan 26. J Immunol. 2011. PMID: 21270393 Free PMC article.

8

The kinase activity of interleukin-1 receptor-associated kinase 2 is essential for lipopolysaccharide-mediated cytokine and chemokine mRNA stability and translation.

Yin W, Wan Y, Kim TW, Yao P, Xiao H, Zhou H, Xiao J, Fox P, Li X. Yin W, et al. Among authors: li x. J Interferon Cytokine Res. 2011 May;31(5):415-22. doi: 10.1089/jir.2010.0094. Epub 2011 Feb 3. J Interferon Cytokine Res. 2011. PMID: 21291324 Free PMC article.

9

SIGIRR, a negative regulator of colon tumorigenesis.

Zhao J, Zepp J, Bulek K, Li X. Zhao J, et al. Among authors: li x. Drug Discov Today Dis Mech. 2011 Winter;8(3-4):e63-e69. doi: 10.1016/j.ddmec.2012.02.003. Epub 2012 Mar 15. Drug Discov Today Dis Mech. 2011. PMID: 22529873 Free PMC article.

10

Pellino 2 is critical for Toll-like receptor/interleukin-1 receptor (TLR/IL-1R)-mediated post-transcriptional control.

Kim TW, Yu M, Zhou H, Cui W, Wang J, DiCorleto P, Fox P, Xiao H, Li X. Kim TW, et al. Among authors: li x. J Biol Chem. 2012 Jul 20;287(30):25686-95. doi: 10.1074/jbc.M112.352625. Epub 2012 Jun 5. J Biol Chem. 2012. PMID: 22669975 Free PMC article.

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