Zhou H - Search Results

1

Inhibition of IRAK4 kinase activity improves ethanol-induced liver injury in mice.

Wang H, Zhou H, Zhang Q, Poulsen KL, Taylor V, McMullen MR, Czarnecki D, Dasarathy D, Yu M, Liao Y, Allende DS, Chen X, Hong L, Zhao J, Yang J, Nagy LE, Li X. Wang H, et al. Among authors: zhou h. J Hepatol. 2020 Dec;73(6):1470-1481. doi: 10.1016/j.jhep.2020.07.016. Epub 2020 Jul 16. J Hepatol. 2020. PMID: 32682051 Free PMC article.

2

IRAKM-Mincle axis links cell death to inflammation: Pathophysiological implications for chronic alcoholic liver disease.

Zhou H, Yu M, Zhao J, Martin BN, Roychowdhury S, McMullen MR, Wang E, Fox PL, Yamasaki S, Nagy LE, Li X. Zhou H, et al. Hepatology. 2016 Dec;64(6):1978-1993. doi: 10.1002/hep.28811. Epub 2016 Oct 25. Hepatology. 2016. PMID: 27628766 Free PMC article.

3

Myeloid-MyD88 Contributes to Ethanol-Induced Liver Injury in Mice Linking Hepatocellular Death to Inflammation.

Zhou H, Yu M, Roychowdhury S, Sanz-Garcia C, Pollard KA, McMullen MR, Liu X, Li X, Nagy LE. Zhou H, et al. Alcohol Clin Exp Res. 2017 Apr;41(4):719-726. doi: 10.1111/acer.13345. Epub 2017 Mar 10. Alcohol Clin Exp Res. 2017. PMID: 28165624 Free PMC article.

4

IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes.

Zhou H, Wang H, Yu M, Schugar RC, Qian W, Tang F, Liu W, Yang H, McDowell RE, Zhao J, Gao J, Dongre A, Carman JA, Yin M, Drazba JA, Dent R, Hine C, Chen YR, Smith JD, Fox PL, Brown JM, Li X. Zhou H, et al. Nat Immunol. 2020 Oct;21(10):1219-1231. doi: 10.1038/s41590-020-0750-1. Epub 2020 Aug 10. Nat Immunol. 2020. PMID: 32778760 Free PMC article.

5

IL-1R-IRAKM-Slc25a1 signaling axis reprograms lipogenesis in adipocytes to promote diet-induced obesity in mice.

Liu W, Zhou H, Wang H, Zhang Q, Zhang R, Willard B, Liu C, Kang Z, Li X, Li X. Liu W, et al. Among authors: zhou h. Nat Commun. 2022 May 18;13(1):2748. doi: 10.1038/s41467-022-30470-w. Nat Commun. 2022. PMID: 35585086 Free PMC article.

6

The dual functions of IL-1 receptor-associated kinase 2 in TLR9-mediated IFN and proinflammatory cytokine production.

Wan Y, Kim TW, Yu M, Zhou H, Yamashita M, Kang Z, Yin W, Wang JA, Thomas J, Sen GC, Stark GR, Li X. Wan Y, et al. Among authors: zhou h. J Immunol. 2011 Mar 1;186(5):3006-14. doi: 10.4049/jimmunol.1003217. Epub 2011 Jan 26. J Immunol. 2011. PMID: 21270393 Free PMC article.

7

Pellino 2 is critical for Toll-like receptor/interleukin-1 receptor (TLR/IL-1R)-mediated post-transcriptional control.

Kim TW, Yu M, Zhou H, Cui W, Wang J, DiCorleto P, Fox P, Xiao H, Li X. Kim TW, et al. Among authors: zhou h. J Biol Chem. 2012 Jul 20;287(30):25686-95. doi: 10.1074/jbc.M112.352625. Epub 2012 Jun 5. J Biol Chem. 2012. PMID: 22669975 Free PMC article.

8

IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production.

Zhou H, Yu M, Fukuda K, Im J, Yao P, Cui W, Bulek K, Zepp J, Wan Y, Kim TW, Yin W, Ma V, Thomas J, Gu J, Wang JA, DiCorleto PE, Fox PL, Qin J, Li X. Zhou H, et al. EMBO J. 2013 Feb 20;32(4):583-96. doi: 10.1038/emboj.2013.2. Epub 2013 Feb 1. EMBO J. 2013. PMID: 23376919 Free PMC article.

9

TH17 cells promote CNS inflammation by sensing danger signals via Mincle.

Zhang Q, Liu W, Wang H, Zhou H, Bulek K, Chen X, Zhang CJ, Zhao J, Zhang R, Liu C, Kang Z, Bermel RA, Dubyak G, Abbott DW, Xiao TS, Nagy LE, Li X. Zhang Q, et al. Among authors: zhou h. Nat Commun. 2022 May 3;13(1):2406. doi: 10.1038/s41467-022-30174-1. Nat Commun. 2022. PMID: 35504893 Free PMC article.

10

Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice.

Zhao J, Bulek K, Gulen MF, Zepp JA, Karagkounis G, Martin BN, Zhou H, Yu M, Liu X, Huang E, Fox PL, Kalady MF, Markowitz SD, Li X. Zhao J, et al. Among authors: zhou h. Gastroenterology. 2015 Dec;149(7):1860-1871.e8. doi: 10.1053/j.gastro.2015.08.051. Epub 2015 Sep 5. Gastroenterology. 2015. PMID: 26344057 Free PMC article.

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