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Systematic Chemogenetic Library Assembly.
Cell Chem Biol. 2020 Sep 17;27(9):1124-1129. doi: 10.1016/j.chembiol.2020.07.004. Epub 2020 Jul 23.
Cell Chem Biol. 2020.
PMID: 32707038
Free article.
Review.
Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders.
Bonazzi S, Goold CP, Gray A, Thomsen NM, Nunez J, Karki RG, Gorde A, Biag JD, Malik HA, Sun Y, Liang G, Lubicka D, Salas S, Labbe-Giguere N, Keaney EP, McTighe S, Liu S, Deng L, Piizzi G, Lombardo F, Burdette D, Dodart JC, Wilson CJ, Peukert S, Curtis D, Hamann LG, Murphy LO.
Bonazzi S, et al. Among authors: labbe giguere n.
J Med Chem. 2020 Feb 13;63(3):1068-1083. doi: 10.1021/acs.jmedchem.9b01398. Epub 2020 Jan 31.
J Med Chem. 2020.
PMID: 31955578
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Identification of Brain-Penetrant ATP-Competitive mTOR Inhibitors for CNS Syndromes.
Bonazzi S, Gray A, Thomsen NM, Biag J, Labbe-Giguere N, Keaney EP, Malik HA, Sun Y, Nunez J, Karki RG, Knapp M, Elling R, Fuller J, Pardee G, Craig L, Capre K, Salas S, Gorde A, Liang G, Lubicka D, McTighe SM, Goold C, Liu S, Deng L, Hong J, Fekete A, Stadelmann P, Frieauff W, Elhajouji A, Bauer D, Lerchner A, Radetich B, Furet P, Piizzi G, Burdette D, Wilson CJ, Peukert S, Hamann LG, Murphy LO, Curtis D.
Bonazzi S, et al. Among authors: labbe giguere n.
J Med Chem. 2023 Jul 13;66(13):9095-9119. doi: 10.1021/acs.jmedchem.3c00705. Epub 2023 Jul 3.
J Med Chem. 2023.
PMID: 37399505
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Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists.
Thomson CG, Boss K, Calhoun A, Fridrich C, Gardinier KM, Hall EC, Jendza K, Kirman L, Labbé-Giguere N, Laumen K, Qian M, Sanyal S, Shultz MD, Snajdrova R, Tan K, Wang KY, Yang F, Gao F, Hong T, Dale E, Kuzmiski B, Ortuno D, Palacios DS.
Thomson CG, et al. Among authors: labbe giguere n.
ACS Med Chem Lett. 2023 Nov 6;14(12):1692-1699. doi: 10.1021/acsmedchemlett.3c00331. eCollection 2023 Dec 14.
ACS Med Chem Lett. 2023.
PMID: 38116445
Free PMC article.
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