Prakash B - Search Results

1

A revised mechanism for (p)ppGpp synthesis by Rel proteins: The critical role of the 2'-OH of GTP.

Patil PR, Vithani N, Singh V, Kumar A, Prakash B. Patil PR, et al. Among authors: prakash b. J Biol Chem. 2020 Sep 11;295(37):12851-12867. doi: 10.1074/jbc.RA120.013636. Epub 2020 Jul 21. J Biol Chem. 2020. PMID: 32719004 Free PMC article.

2

Substrate-bound crystal structures reveal features unique to Mycobacterium tuberculosis N-acetyl-glucosamine 1-phosphate uridyltransferase and a catalytic mechanism for acetyl transfer.

Jagtap PK, Soni V, Vithani N, Jhingan GD, Bais VS, Nandicoori VK, Prakash B. Jagtap PK, et al. Among authors: prakash b. J Biol Chem. 2012 Nov 16;287(47):39524-37. doi: 10.1074/jbc.M112.390765. Epub 2012 Sep 11. J Biol Chem. 2012. PMID: 22969087 Free PMC article.

3

Purification and preliminary characterization of four Rel homologues from pathogenic bacteria: Implications for species-specific inhibitor design.

Hegde V, Raman AS, Patil PR, Prakash B. Hegde V, et al. Among authors: prakash b. Protein Expr Purif. 2021 Jan;177:105760. doi: 10.1016/j.pep.2020.105760. Epub 2020 Sep 29. Protein Expr Purif. 2021. PMID: 33002609

4

Crystal structures identify an atypical two-metal-ion mechanism for uridyltransfer in GlmU: its significance to sugar nucleotidyl transferases.

Jagtap PK, Verma SK, Vithani N, Bais VS, Prakash B. Jagtap PK, et al. Among authors: prakash b. J Mol Biol. 2013 May 27;425(10):1745-59. doi: 10.1016/j.jmb.2013.02.019. Epub 2013 Feb 26. J Mol Biol. 2013. PMID: 23485416

5

Identification and characterization of a hitherto unknown nucleotide-binding domain and an intricate interdomain regulation in HflX-a ribosome binding GTPase.

Jain N, Vithani N, Rafay A, Prakash B. Jain N, et al. Among authors: prakash b. Nucleic Acids Res. 2013 Nov;41(20):9557-69. doi: 10.1093/nar/gkt705. Epub 2013 Aug 16. Nucleic Acids Res. 2013. PMID: 23956218 Free PMC article.

6

GlmU (N-acetylglucosamine-1-phosphate uridyltransferase) bound to three magnesium ions and ATP at the active site.

Vithani N, Bais V, Prakash B. Vithani N, et al. Among authors: prakash b. Acta Crystallogr F Struct Biol Commun. 2014 Jun;70(Pt 6):703-8. doi: 10.1107/S2053230X14008279. Epub 2014 May 10. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 24915076 Free PMC article.

7

Mechanism of Mg²⁺-Accompanied Product Release in Sugar Nucleotidyltransferases.

Vithani N, Ankush Jagtap PK, Verma SK, Tripathi R, Awasthi S, Nair NN, Prakash B. Vithani N, et al. Among authors: prakash b. Structure. 2018 Mar 6;26(3):459-466.e3. doi: 10.1016/j.str.2018.02.002. Structure. 2018. PMID: 29514078 Free article.

8

Mechanism of Nucleotidyltransfer Reaction and Role of Mg²⁺ Ion in Sugar Nucleotidyltransferases.

Vithani N, Prakash B, Nair NN. Vithani N, et al. Among authors: prakash b. Biophys J. 2020 Aug 4;119(3):619-627. doi: 10.1016/j.bpj.2020.06.017. Epub 2020 Jun 24. Biophys J. 2020. PMID: 32645293 Free PMC article.

9

A charge reversal differentiates (p)ppGpp synthesis by monofunctional and bifunctional Rel proteins.

Sajish M, Tiwari D, Rananaware D, Nandicoori VK, Prakash B. Sajish M, et al. Among authors: prakash b. J Biol Chem. 2007 Nov 30;282(48):34977-83. doi: 10.1074/jbc.M704828200. Epub 2007 Oct 2. J Biol Chem. 2007. PMID: 17911108 Free article.

10

A salt-bridge stabilized C-terminal hook is critical for the dimerization of a Bowman Birk inhibitor.

Kumar V, Murugeson S, Vithani N, Prakash B, Gowda LR. Kumar V, et al. Among authors: prakash b. Arch Biochem Biophys. 2015 Jan 15;566:15-25. doi: 10.1016/j.abb.2014.12.011. Epub 2014 Dec 16. Arch Biochem Biophys. 2015. PMID: 25527163

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