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Biology, pathology, and therapeutic targeting of RAS.
Rhett JM, Khan I, O'Bryan JP. Rhett JM, et al. Among authors: khan i. Adv Cancer Res. 2020;148:69-146. doi: 10.1016/bs.acr.2020.05.002. Epub 2020 Jul 9. Adv Cancer Res. 2020. PMID: 32723567 Free PMC article. Review.
Inhibition of RAS: proven and potential vulnerabilities.
Zuberi M, Khan I, O'Bryan JP. Zuberi M, et al. Among authors: khan i. Biochem Soc Trans. 2020 Oct 30;48(5):1831-1841. doi: 10.1042/BST20190023. Biochem Soc Trans. 2020. PMID: 32869838 Free PMC article. Review.
Probing RAS Function with Monobodies.
Khan I, O'Bryan JP. Khan I, et al. Methods Mol Biol. 2021;2262:281-302. doi: 10.1007/978-1-0716-1190-6_17. Methods Mol Biol. 2021. PMID: 33977484 Free PMC article.
Targeting the "undruggable" RAS with biologics.
Whaby M, Khan I, O'Bryan JP. Whaby M, et al. Among authors: khan i. Adv Cancer Res. 2022;153:237-266. doi: 10.1016/bs.acr.2021.07.006. Epub 2021 Aug 13. Adv Cancer Res. 2022. PMID: 35101232 Free PMC article. Review.
Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK pathway.
Sofi MH, Tian L, Schutt S, Khan I, Choi HJ, Wu Y, Bastian D, Ticer T, Kassir MF, Atilgan FC, Kim J, Sui X, Zivkovic A, Mehrotra S, O'Bryan JP, Stark H, Martin PJ, Ogretmen B, Yu XZ. Sofi MH, et al. Among authors: khan i. Leukemia. 2022 Jul;36(7):1907-1915. doi: 10.1038/s41375-022-01581-6. Epub 2022 May 5. Leukemia. 2022. PMID: 35513703 Free PMC article.
6,339 results