Mitrović A - Search Results

1

Synthesis of Novel Nitroxoline Analogs with Potent Cathepsin B Exopeptidase Inhibitory Activity.

Van de Walle T, Briand M, Mitrović A, Sosič I, Gobec S, Kos J, Persoons L, Daelemans D, De Jonghe S, Ubiparip Z, Desmet T, Van Hecke K, Mangelinckx S, D'hooghe M. Van de Walle T, et al. Among authors: mitrovic a. ChemMedChem. 2020 Dec 15;15(24):2477-2490. doi: 10.1002/cmdc.202000402. Epub 2020 Sep 21. ChemMedChem. 2020. PMID: 32744405

2

The current stage of cathepsin B inhibitors as potential anticancer agents.

Kos J, Mitrović A, Mirković B. Kos J, et al. Among authors: mitrovic a. Future Med Chem. 2014 Jul;6(11):1355-71. doi: 10.4155/fmc.14.73. Future Med Chem. 2014. PMID: 25163003 Review.

3

Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity.

Mirković B, Markelc B, Butinar M, Mitrović A, Sosič I, Gobec S, Vasiljeva O, Turk B, Čemažar M, Serša G, Kos J. Mirković B, et al. Among authors: mitrovic a. Oncotarget. 2015 Aug 7;6(22):19027-42. doi: 10.18632/oncotarget.3699. Oncotarget. 2015. PMID: 25848918 Free PMC article.

4

Inhibition of endopeptidase and exopeptidase activity of cathepsin B impairs extracellular matrix degradation and tumour invasion.

Mitrović A, Mirković B, Sosič I, Gobec S, Kos J. Mitrović A, et al. Biol Chem. 2016 Jan 1;397(2):165-74. doi: 10.1515/hsz-2015-0236. Biol Chem. 2016. PMID: 26565553

5

Clioquinol-ruthenium complex impairs tumour cell invasion by inhibiting cathepsin B activity.

Mitrović A, Kljun J, Sosič I, Gobec S, Turel I, Kos J. Mitrović A, et al. Dalton Trans. 2016 Nov 14;45(42):16913-16921. doi: 10.1039/c6dt02369j. Epub 2016 Sep 30. Dalton Trans. 2016. PMID: 27711842

6

Cysteine cathepsins B and X promote epithelial-mesenchymal transition of tumor cells.

Mitrović A, Pečar Fonović U, Kos J. Mitrović A, et al. Eur J Cell Biol. 2017 Sep;96(6):622-631. doi: 10.1016/j.ejcb.2017.04.003. Epub 2017 Apr 25. Eur J Cell Biol. 2017. PMID: 28495172

7

Identification and characterization of the novel reversible and selective cathepsin X inhibitors.

Fonović UP, Mitrović A, Knez D, Jakoš T, Pišlar A, Brus B, Doljak B, Stojan J, Žakelj S, Trontelj J, Gobec S, Kos J. Fonović UP, et al. Among authors: mitrovic a. Sci Rep. 2017 Sep 13;7(1):11459. doi: 10.1038/s41598-017-11935-1. Sci Rep. 2017. PMID: 28904354 Free PMC article.

8

Addition of 2-(ethylamino)acetonitrile group to nitroxoline results in significantly improved anti-tumor activity in vitro and in vivo.

Mitrović A, Sosič I, Kos Š, Tratar UL, Breznik B, Kranjc S, Mirković B, Gobec S, Lah T, Serša G, Kos J. Mitrović A, et al. Oncotarget. 2017 Jul 17;8(35):59136-59147. doi: 10.18632/oncotarget.19296. eCollection 2017 Aug 29. Oncotarget. 2017. PMID: 28938624 Free PMC article.

9

Cathepsin B inhibitors: Further exploration of the nitroxoline core.

Sosič I, Mitrović A, Ćurić H, Knez D, Brodnik Žugelj H, Štefane B, Kos J, Gobec S. Sosič I, et al. Among authors: mitrovic a. Bioorg Med Chem Lett. 2018 Apr 15;28(7):1239-1247. doi: 10.1016/j.bmcl.2018.02.042. Epub 2018 Feb 23. Bioorg Med Chem Lett. 2018. PMID: 29503024

10

A road map for prioritizing warheads for cysteine targeting covalent inhibitors.

Ábrányi-Balogh P, Petri L, Imre T, Szijj P, Scarpino A, Hrast M, Mitrović A, Fonovič UP, Németh K, Barreteau H, Roper DI, Horváti K, Ferenczy GG, Kos J, Ilaš J, Gobec S, Keserű GM. Ábrányi-Balogh P, et al. Among authors: mitrovic a. Eur J Med Chem. 2018 Dec 5;160:94-107. doi: 10.1016/j.ejmech.2018.10.010. Epub 2018 Oct 6. Eur J Med Chem. 2018. PMID: 30321804

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