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Selective inhibition of mTORC1 in tumor vessels increases antitumor immunity.
Wang S, Raybuck A, Shiuan E, Cho SH, Wang Q, Brantley-Sieders DM, Edwards D, Allaman MM, Nathan J, Wilson KT, DeNardo D, Zhang S, Cook R, Boothby M, Chen J. Wang S, et al. Among authors: cook r. JCI Insight. 2020 Aug 6;5(15):e139237. doi: 10.1172/jci.insight.139237. JCI Insight. 2020. PMID: 32759497 Free PMC article.
Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC.
Amato KR, Wang S, Hastings AK, Youngblood VM, Santapuram PR, Chen H, Cates JM, Colvin DC, Ye F, Brantley-Sieders DM, Cook RS, Tan L, Gray NS, Chen J. Amato KR, et al. Among authors: cook rs. J Clin Invest. 2014 May;124(5):2037-49. doi: 10.1172/JCI72522. Epub 2014 Apr 8. J Clin Invest. 2014. PMID: 24713656 Free PMC article.
Activating PIK3CA Mutations Induce an Epidermal Growth Factor Receptor (EGFR)/Extracellular Signal-regulated Kinase (ERK) Paracrine Signaling Axis in Basal-like Breast Cancer.
Young CD, Zimmerman LJ, Hoshino D, Formisano L, Hanker AB, Gatza ML, Morrison MM, Moore PD, Whitwell CA, Dave B, Stricker T, Bhola NE, Silva GO, Patel P, Brantley-Sieders DM, Levin M, Horiates M, Palma NA, Wang K, Stephens PJ, Perou CM, Weaver AM, O'Shaughnessy JA, Chang JC, Park BH, Liebler DC, Cook RS, Arteaga CL. Young CD, et al. Mol Cell Proteomics. 2015 Jul;14(7):1959-76. doi: 10.1074/mcp.M115.049783. Epub 2015 May 7. Mol Cell Proteomics. 2015. PMID: 25953087 Free PMC article. Clinical Trial.
3,542 results