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Determination of novel CYP2D6 haplotype using the targeted sequencing followed by the long-read sequencing and the functional characterization in the Japanese population.
Fukunaga K, Hishinuma E, Hiratsuka M, Kato K, Okusaka T, Saito T, Ikeda M, Yoshida T, Zembutsu H, Iwata N, Mushiroda T. Fukunaga K, et al. Among authors: hishinuma e. J Hum Genet. 2021 Feb;66(2):139-149. doi: 10.1038/s10038-020-0815-x. Epub 2020 Aug 5. J Hum Genet. 2021. PMID: 32759992
Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation.
Watanabe T, Saito T, Rico EMG, Hishinuma E, Kumondai M, Maekawa M, Oda A, Saigusa D, Saito S, Yasuda J, Nagasaki M, Minegishi N, Yamamoto M, Yamaguchi H, Mano N, Hirasawa N, Hiratsuka M. Watanabe T, et al. Among authors: hishinuma e. Biochem Pharmacol. 2018 Oct;156:420-430. doi: 10.1016/j.bcp.2018.09.010. Epub 2018 Sep 8. Biochem Pharmacol. 2018. PMID: 30201214
Development and application of a rapid and sensitive genotyping method for pharmacogene variants using the single-stranded tag hybridization chromatographic printed-array strip (STH-PAS).
Kumondai M, Ito A, Hishinuma E, Kikuchi A, Saito T, Takahashi M, Tsukada C, Saito S, Yasuda J, Nagasaki M, Minegishi N, Yamamoto M, Kaneko A, Teramoto I, Kimura M, Hirasawa N, Hiratsuka M. Kumondai M, et al. Among authors: hishinuma e. Drug Metab Pharmacokinet. 2018 Dec;33(6):258-263. doi: 10.1016/j.dmpk.2018.08.003. Epub 2018 Aug 22. Drug Metab Pharmacokinet. 2018. PMID: 30269962
Genetic variants of flavin-containing monooxygenase 3 (FMO3) derived from Japanese subjects with the trimethylaminuria phenotype and whole-genome sequence data from a large Japanese database.
Shimizu M, Yoda H, Nakakuki K, Saso A, Saito I, Hishinuma E, Saito S, Hiratsuka M, Yamazaki H. Shimizu M, et al. Among authors: hishinuma e. Drug Metab Pharmacokinet. 2019 Oct;34(5):334-339. doi: 10.1016/j.dmpk.2019.06.001. Epub 2019 Jun 27. Drug Metab Pharmacokinet. 2019. PMID: 31401033
CYP2D6 genotyping analysis and functional characterization of novel allelic variants in a Ni-Vanuatu and Kenyan population by assessing dextromethorphan O-demethylation activity.
Gutiérrez Rico EM, Kikuchi A, Saito T, Kumondai M, Hishinuma E, Kaneko A, Chan CW, Gitaka J, Nakayoshi T, Oda A, Saito S, Hirasawa N, Hiratsuka M. Gutiérrez Rico EM, et al. Among authors: hishinuma e. Drug Metab Pharmacokinet. 2020 Feb;35(1):89-101. doi: 10.1016/j.dmpk.2019.07.003. Epub 2019 Jul 20. Drug Metab Pharmacokinet. 2020. PMID: 32037159
134 results