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A meta-analysis of the effects of early life stress on the prefrontal cortex transcriptome suggests long-term effects on myelin.
Duan TQ, Hagenauer MH, Flandreau EI, Bader A, Nguyen DM, Maras PM, De Lima RMS, Gyles T, Mclain C, Meaney MJ, Nestler EJ, Watson SJ Jr, Akil H. Duan TQ, et al. Among authors: watson sj jr. bioRxiv [Preprint]. 2024 Nov 24:2024.11.22.624315. doi: 10.1101/2024.11.22.624315. bioRxiv. 2024. PMID: 39605735 Free PMC article. Preprint.
Resource: A curated database of brain-related functional gene sets (Brain.GMT).
Hagenauer MH, Sannah Y, Hebda-Bauer EK, Rhoads C, O'Connor AM, Flandreau E, Watson SJ Jr, Akil H. Hagenauer MH, et al. Among authors: watson sj jr. MethodsX. 2024 Jun 24;13:102788. doi: 10.1016/j.mex.2024.102788. eCollection 2024 Dec. MethodsX. 2024. PMID: 39049932 Free PMC article.
Adolescent environmental enrichment induces social resilience and alters neural gene expression in a selectively bred rodent model with anxious phenotype.
O'Connor AM, Hagenauer MH, Thew Forrester LC, Maras PM, Arakawa K, Hebda-Bauer EK, Khalil H, Richardson ER, Rob FI, Sannah Y, Watson SJ Jr, Akil H. O'Connor AM, et al. Among authors: watson sj jr. Neurobiol Stress. 2024 May 30;31:100651. doi: 10.1016/j.ynstr.2024.100651. eCollection 2024 Jul. Neurobiol Stress. 2024. PMID: 38933284 Free PMC article.
Adolescent environmental enrichment induces social resilience and alters neural gene expression in a selectively bred rodent model with anxious phenotype.
O'Connor AM, Hagenauer MH, Forrester LCT, Maras PM, Arakawa K, Hebda-Bauer EK, Khalil H, Richardson ER, Rob FI, Sannah Y, Watson SJ Jr, Akil H. O'Connor AM, et al. Among authors: watson sj jr. bioRxiv [Preprint]. 2024 Apr 11:2023.10.03.560702. doi: 10.1101/2023.10.03.560702. bioRxiv. 2024. Update in: Neurobiol Stress. 2024 May 30;31:100651. doi: 10.1016/j.ynstr.2024.100651 PMID: 38645129 Free PMC article. Updated. Preprint.
The impact of COVID-19 on a college freshman sample reveals genetic and nongenetic forms of susceptibility and resilience to stress.
Turner CA, Khalil H, Murphy-Weinberg V, Hagenauer MH, Gates L, Tang Y, Weinberg L, Grysko R, Floran-Garduno L, Dokas T, Samaniego C, Zhao Z, Fang Y, Sen S, Lopez JF, Watson SJ Jr, Akil H. Turner CA, et al. Among authors: watson sj jr. Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2305779120. doi: 10.1073/pnas.2305779120. Epub 2023 Nov 27. Proc Natl Acad Sci U S A. 2023. PMID: 38011555 Free PMC article.
Neurotransmission-related gene expression in the frontal pole is altered in subjects with bipolar disorder and schizophrenia.
Medina AM, Hagenauer MH, Krolewski DM, Hughes E, Forrester LCT, Walsh DM, Waselus M, Richardson E, Turner CA, Sequeira PA, Cartagena PM, Thompson RC, Vawter MP, Bunney BG, Myers RM, Barchas JD, Lee FS, Schatzberg AF, Bunney WE, Akil H, Watson SJ Jr. Medina AM, et al. Among authors: watson sj jr. Transl Psychiatry. 2023 Apr 8;13(1):118. doi: 10.1038/s41398-023-02418-1. Transl Psychiatry. 2023. PMID: 37031222 Free PMC article.
Genome-wide association study in a rat model of temperament identifies multiple loci for exploratory locomotion and anxiety-like traits.
Chitre AS, Hebda-Bauer EK, Blandino P, Bimschleger H, Nguyen KM, Maras P, Li F, Ozel AB, Pan Y, Polesskaya O, Cheng R, Flagel SB, Watson SJ Jr, Li J, Akil H, Palmer AA. Chitre AS, et al. Among authors: watson sj jr. Front Genet. 2023 Jan 11;13:1003074. doi: 10.3389/fgene.2022.1003074. eCollection 2022. Front Genet. 2023. PMID: 36712851 Free PMC article.
Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model.
Birt IA, Hagenauer MH, Clinton SM, Aydin C, Blandino P Jr, Stead JDH, Hilde KL, Meng F, Thompson RC, Khalil H, Stefanov A, Maras P, Zhou Z, Hebda-Bauer EK, Goldman D, Watson SJ Jr, Akil H. Birt IA, et al. Among authors: watson sj jr. Biol Psychiatry. 2021 Feb 15;89(4):339-355. doi: 10.1016/j.biopsych.2020.05.024. Epub 2020 May 27. Biol Psychiatry. 2021. PMID: 32762937 Free PMC article.
48 results