Griffett K - Search Results

1

The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids.

Griffett K, Bedia-Diaz G, Hegazy L, de Vera IMS, Wanninayake US, Billon C, Koelblen T, Wilhelm ML, Burris TP. Griffett K, et al. Cell Chem Biol. 2020 Oct 15;27(10):1272-1284.e4. doi: 10.1016/j.chembiol.2020.07.013. Epub 2020 Aug 6. Cell Chem Biol. 2020. PMID: 32763139 Free article.

2

A liver-selective LXR inverse agonist that suppresses hepatic steatosis.

Griffett K, Solt LA, El-Gendy Bel-D, Kamenecka TM, Burris TP. Griffett K, et al. ACS Chem Biol. 2013 Mar 15;8(3):559-67. doi: 10.1021/cb300541g. Epub 2012 Dec 27. ACS Chem Biol. 2013. PMID: 23237488

3

Nuclear receptors and their selective pharmacologic modulators.

Burris TP, Solt LA, Wang Y, Crumbley C, Banerjee S, Griffett K, Lundasen T, Hughes T, Kojetin DJ. Burris TP, et al. Among authors: griffett k. Pharmacol Rev. 2013 Mar 1;65(2):710-78. doi: 10.1124/pr.112.006833. Print 2013 Apr. Pharmacol Rev. 2013. PMID: 23457206 Free PMC article. Review.

4

The mammalian clock and chronopharmacology.

Griffett K, Burris TP. Griffett K, et al. Bioorg Med Chem Lett. 2013 Apr 1;23(7):1929-34. doi: 10.1016/j.bmcl.2013.02.015. Epub 2013 Feb 13. Bioorg Med Chem Lett. 2013. PMID: 23481644 Free PMC article. Review.

5

Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour.

Banerjee S, Wang Y, Solt LA, Griffett K, Kazantzis M, Amador A, El-Gendy BM, Huitron-Resendiz S, Roberts AJ, Shin Y, Kamenecka TM, Burris TP. Banerjee S, et al. Among authors: griffett k. Nat Commun. 2014 Dec 23;5:5759. doi: 10.1038/ncomms6759. Nat Commun. 2014. PMID: 25536025 Free PMC article.

6

The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis.

Griffett K, Welch RD, Flaveny CA, Kolar GR, Neuschwander-Tetri BA, Burris TP. Griffett K, et al. Mol Metab. 2015 Feb 9;4(4):353-7. doi: 10.1016/j.molmet.2015.01.009. eCollection 2015 Apr. Mol Metab. 2015. PMID: 25830098 Free PMC article.

7

Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis.

Flaveny CA, Griffett K, El-Gendy Bel-D, Kazantzis M, Sengupta M, Amelio AL, Chatterjee A, Walker J, Solt LA, Kamenecka TM, Burris TP. Flaveny CA, et al. Among authors: griffett k. Cancer Cell. 2015 Jul 13;28(1):42-56. doi: 10.1016/j.ccell.2015.05.007. Epub 2015 Jun 25. Cancer Cell. 2015. PMID: 26120082 Free PMC article.

8

Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver disease.

Griffett K, Burris TP. Griffett K, et al. Biochem Biophys Res Commun. 2016 Oct 21;479(3):424-428. doi: 10.1016/j.bbrc.2016.09.036. Epub 2016 Sep 25. Biochem Biophys Res Commun. 2016. PMID: 27680310 Free PMC article.

9

Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold.

Goher SS, Griffett K, Hegazy L, Elagawany M, Arief MMH, Avdagic A, Banerjee S, Burris TP, Elgendy B. Goher SS, et al. Among authors: griffett k. Bioorg Med Chem Lett. 2019 Feb 1;29(3):449-453. doi: 10.1016/j.bmcl.2018.12.025. Epub 2018 Dec 15. Bioorg Med Chem Lett. 2019. PMID: 30587446

10

Inhibition of Hepatotoxicity by a LXR Inverse Agonist in a Model of Alcoholic Liver Disease.

Sengupta M, Griffett K, Flaveny CA, Burris TP. Sengupta M, et al. Among authors: griffett k. ACS Pharmacol Transl Sci. 2018 Sep 14;1(1):50-60. doi: 10.1021/acsptsci.8b00003. Epub 2018 Jul 25. ACS Pharmacol Transl Sci. 2018. PMID: 31696159 Free PMC article.

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