Gaedigk A - Search Results

1

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing.

Lima JJ, Thomas CD, Barbarino J, Desta Z, Van Driest SL, El Rouby N, Johnson JA, Cavallari LH, Shakhnovich V, Thacker DL, Scott SA, Schwab M, Uppugunduri CRS, Formea CM, Franciosi JP, Sangkuhl K, Gaedigk A, Klein TE, Gammal RS, Furuta T. Lima JJ, et al. Among authors: gaedigk a. Clin Pharmacol Ther. 2021 Jun;109(6):1417-1423. doi: 10.1002/cpt.2015. Epub 2020 Sep 20. Clin Pharmacol Ther. 2021. PMID: 32770672 Free PMC article.

2

Interethnic differences of drug-metabolizing enzymes.

Gaedigk A. Gaedigk A. Int J Clin Pharmacol Ther. 2000 Feb;38(2):61-8. doi: 10.5414/cpp38061. Int J Clin Pharmacol Ther. 2000. PMID: 10706192 Review.

3

Effect of sex and menstrual cycle phase on cytochrome P450 2C19 activity with omeprazole used as a biomarker.

Kim MJ, Bertino JS Jr, Gaedigk A, Zhang Y, Sellers EM, Nafziger AN. Kim MJ, et al. Among authors: gaedigk a. Clin Pharmacol Ther. 2002 Aug;72(2):192-9. doi: 10.1067/mcp.2002.126174. Clin Pharmacol Ther. 2002. PMID: 12189366

4

Omeprazole disposition in children following single-dose administration.

Kearns GL, Andersson T, James LP, Gaedigk A, Kraynak RA, Abdel-Rahman SM, Ramabadran K, van den Anker JN. Kearns GL, et al. Among authors: gaedigk a. J Clin Pharmacol. 2003 Aug;43(8):840-8. doi: 10.1177/0091270003256122. J Clin Pharmacol. 2003. PMID: 12953341 Clinical Trial.

5

Pharmacokinetics and CYP2D6 genotypes do not predict metoprolol adverse events or efficacy in hypertension.

Zineh I, Beitelshees AL, Gaedigk A, Walker JR, Pauly DF, Eberst K, Leeder JS, Phillips MS, Gelfand CA, Johnson JA. Zineh I, et al. Among authors: gaedigk a. Clin Pharmacol Ther. 2004 Dec;76(6):536-44. doi: 10.1016/j.clpt.2004.08.020. Clin Pharmacol Ther. 2004. PMID: 15592325

6

Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events.

Gaedigk A, Ndjountché L, Divakaran K, Dianne Bradford L, Zineh I, Oberlander TF, Brousseau DC, McCarver DG, Johnson JA, Alander SW, Wayne Riggs K, Steven Leeder J. Gaedigk A, et al. Clin Pharmacol Ther. 2007 Feb;81(2):242-51. doi: 10.1038/sj.clpt.6100033. Clin Pharmacol Ther. 2007. PMID: 17259947

7

Ontogeny of dextromethorphan O- and N-demethylation in the first year of life.

Blake MJ, Gaedigk A, Pearce RE, Bomgaars LR, Christensen ML, Stowe C, James LP, Wilson JT, Kearns GL, Leeder JS. Blake MJ, et al. Among authors: gaedigk a. Clin Pharmacol Ther. 2007 Apr;81(4):510-6. doi: 10.1038/sj.clpt.6100101. Epub 2007 Feb 14. Clin Pharmacol Ther. 2007. PMID: 17301735

8

Identification and characterization of CYP2D6*56B, an allele associated with the poor metabolizer phenotype.

Gaedigk A, Eklund JD, Pearce RE, Leeder JS, Alander SW, Phillips MS, Bradford LD, Kennedy MJ. Gaedigk A, et al. Clin Pharmacol Ther. 2007 Jun;81(6):817-20. doi: 10.1038/sj.clpt.6100125. Epub 2007 Mar 28. Clin Pharmacol Ther. 2007. PMID: 17392730

9

Single-dose pharmacokinetics of oral and intravenous pantoprazole in children and adolescents.

Kearns GL, Blumer J, Schexnayder S, James LP, Adcock KG, Reed MD, Daniel JF, Gaedigk A, Paul J. Kearns GL, et al. Among authors: gaedigk a. J Clin Pharmacol. 2008 Nov;48(11):1356-65. doi: 10.1177/0091270008321811. Epub 2008 Jul 29. J Clin Pharmacol. 2008. PMID: 18664620 Clinical Trial.

10

Pharmacogenetics of neonatal opioid toxicity following maternal use of codeine during breastfeeding: a case-control study.

Madadi P, Ross CJ, Hayden MR, Carleton BC, Gaedigk A, Leeder JS, Koren G. Madadi P, et al. Among authors: gaedigk a. Clin Pharmacol Ther. 2009 Jan;85(1):31-5. doi: 10.1038/clpt.2008.157. Epub 2008 Aug 20. Clin Pharmacol Ther. 2009. PMID: 18719619

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