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Integrating Dynamic Positron Emission Tomography and Conventional Pharmacokinetic Studies to Delineate Plasma and Tumor Pharmacokinetics of FAU, a Prodrug Bioactivated by Thymidylate Synthase.
Li J, Kim S, Shields AF, Douglas KA, McHugh CI, Lawhorn-Crews JM, Wu J, Mangner TJ, LoRusso PM. Li J, et al. Among authors: wu j. J Clin Pharmacol. 2016 Nov;56(11):1433-1447. doi: 10.1002/jcph.751. J Clin Pharmacol. 2016. PMID: 27095537 Free PMC article. Clinical Trial.
An aqueous normal-phase chromatography coupled with tandem mass spectrometry method for determining unbound brain-to-plasma concentration ratio of AZD1775, a Wee1 kinase inhibitor, in patients with glioblastoma.
Wu J, Sanai N, Bao X, LoRusso P, Li J. Wu J, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Aug 15;1028:25-32. doi: 10.1016/j.jchromb.2016.05.050. Epub 2016 Jun 3. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 27318641 Free PMC article. Clinical Trial.
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