Engman H - Search Results

1

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.

Ahmad A, Pepin X, Aarons L, Wang Y, Darwich AS, Wood JM, Tannergren C, Karlsson E, Patterson C, Thörn H, Ruston L, Mattinson A, Carlert S, Berg S, Murphy D, Engman H, Laru J, Barker R, Flanagan T, Abrahamsson B, Budhdeo S, Franek F, Moir A, Hanisch G, Pathak SM, Turner D, Jamei M, Brown J, Good D, Vaidhyanathan S, Jackson C, Nicolas O, Beilles S, Nguefack JF, Louit G, Henrion L, Ollier C, Boulu L, Xu C, Heimbach T, Ren X, Lin W, Nguyen-Trung AT, Zhang J, He H, Wu F, Bolger MB, Mullin JM, van Osdol B, Szeto K, Korjamo T, Pappinen S, Tuunainen J, Zhu W, Xia B, Daublain P, Wong S, Varma MVS, Modi S, Schäfer KJ, Schmid K, Lloyd R, Patel A, Tistaert C, Bevernage J, Nguyen MA, Lindley D, Carr R, Rostami-Hodjegan A. Ahmad A, et al. Among authors: engman h. Eur J Pharm Biopharm. 2020 Nov;156:50-63. doi: 10.1016/j.ejpb.2020.08.006. Epub 2020 Aug 14. Eur J Pharm Biopharm. 2020. PMID: 32805361

2

Enantioselective transport and CYP3A4-mediated metabolism of R/S-verapamil in Caco-2 cell monolayers.

Engman H, Tannergren C, Artursson P, Lennernäs H. Engman H, et al. Eur J Pharm Sci. 2003 May;19(1):57-65. doi: 10.1016/s0928-0987(03)00065-4. Eur J Pharm Sci. 2003. PMID: 12729862

3

St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism.

Tannergren C, Engman H, Knutson L, Hedeland M, Bondesson U, Lennernäs H. Tannergren C, et al. Among authors: engman h. Clin Pharmacol Ther. 2004 Apr;75(4):298-309. doi: 10.1016/j.clpt.2003.12.012. Clin Pharmacol Ther. 2004. PMID: 15060508 Clinical Trial.

4

CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies.

Engman HA, Lennernäs H, Taipalensuu J, Otter C, Leidvik B, Artursson P. Engman HA, et al. J Pharm Sci. 2001 Nov;90(11):1736-51. doi: 10.1002/jps.1123. J Pharm Sci. 2001. PMID: 11745731

5

Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes.

Gaillard PJ, Voorwinden LH, Nielsen JL, Ivanov A, Atsumi R, Engman H, Ringbom C, de Boer AG, Breimer DD. Gaillard PJ, et al. Among authors: engman h. Eur J Pharm Sci. 2001 Jan;12(3):215-22. doi: 10.1016/s0928-0987(00)00123-8. Eur J Pharm Sci. 2001. PMID: 11113640

6

Bioequivalence and Food Effect of Dapagliflozin/Saxagliptin/Metformin Extended-release Fixed-combination Drug Products Compared With Coadministration of the Individual Components in Healthy Subjects.

Tang W, Engman H, Zhu Y, Dayton B, Boulton DW. Tang W, et al. Among authors: engman h. Clin Ther. 2019 Aug;41(8):1545-1563. doi: 10.1016/j.clinthera.2019.05.015. Epub 2019 Jun 29. Clin Ther. 2019. PMID: 31266654 Clinical Trial.

7

Engineering protein thermostability using a generic activity-independent biophysical screen inside the cell.

Asial I, Cheng YX, Engman H, Dollhopf M, Wu B, Nordlund P, Cornvik T. Asial I, et al. Among authors: engman h. Nat Commun. 2013;4:2901. doi: 10.1038/ncomms3901. Nat Commun. 2013. PMID: 24352381 Free article.

8

Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA.

Guskov A, Nordin N, Reynaud A, Engman H, Lundbäck AK, Jong AJ, Cornvik T, Phua T, Eshaghi S. Guskov A, et al. Among authors: engman h. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18459-64. doi: 10.1073/pnas.1210076109. Epub 2012 Oct 22. Proc Natl Acad Sci U S A. 2012. PMID: 23091000 Free PMC article.

9

HF-EPR, Raman, UV/VIS light spectroscopic, and DFT studies of the ribonucleotide reductase R2 tyrosyl radical from Epstein-Barr virus.

Tomter AB, Zoppellaro G, Schmitzberger F, Andersen NH, Barra AL, Engman H, Nordlund P, Andersson KK. Tomter AB, et al. Among authors: engman h. PLoS One. 2011;6(9):e25022. doi: 10.1371/journal.pone.0025022. Epub 2011 Sep 27. PLoS One. 2011. PMID: 21980375 Free PMC article.

10

A systematic approach to isolate mono-disperse membrane proteins - purification of zinc transporter ZntB.

Van Pham ST, Engman H, Dahlgren LG, Cornvik T, Eshaghi S. Van Pham ST, et al. Among authors: engman h. Protein Expr Purif. 2010 Jul;72(1):48-54. doi: 10.1016/j.pep.2010.02.006. Epub 2010 Feb 14. Protein Expr Purif. 2010. PMID: 20159043

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