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Complete biosynthesis of QS-21 in engineered yeast.
Liu Y, Zhao X, Gan F, Chen X, Deng K, Crowe SA, Hudson GA, Belcher MS, Schmidt M, Astolfi MCT, Kosina SM, Pang B, Shao M, Yin J, Sirirungruang S, Iavarone AT, Reed J, Martin LBB, El-Demerdash A, Kikuchi S, Misra RC, Liang X, Cronce MJ, Chen X, Zhan C, Kakumanu R, Baidoo EEK, Chen Y, Petzold CJ, Northen TR, Osbourn A, Scheller H, Keasling JD. Liu Y, et al. Nature. 2024 May;629(8013):937-944. doi: 10.1038/s41586-024-07345-9. Epub 2024 May 8. Nature. 2024. PMID: 38720067 Free PMC article.