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Page 1
The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro.
Yaron TM, Heaton BE, Levy TM, Johnson JL, Jordan TX, Cohen BM, Kerelsky A, Lin TY, Liberatore KM, Bulaon DK, Kastenhuber ER, Mercadante MN, Shobana-Ganesh K, He L, Schwartz RE, Chen S, Weinstein H, Elemento O, Piskounova E, Nilsson-Payant BE, Lee G, Trimarco JD, Burke KN, Hamele CE, Chaparian RR, Harding AT, Tata A, Zhu X, Tata PR, Smith CM, Possemato AP, Tkachev SL, Hornbeck PV, Beausoleil SA, Anand SK, Aguet F, Getz G, Davidson AD, Heesom K, Kavanagh-Williamson M, Matthews D, tenOever BR, Cantley LC, Blenis J, Heaton NS. Yaron TM, et al. Among authors: elemento o. bioRxiv [Preprint]. 2020 Dec 16:2020.08.14.251207. doi: 10.1101/2020.08.14.251207. bioRxiv. 2020. PMID: 32817937 Free PMC article. Preprint.
HLA-E and NKG2A Mediate Resistance to M. bovis BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer.
Ranti D, Yu H, Wang YA, Bieber C, Strandgaard T, Salomé B, Houghton S, Kim J, Ravichandran H, Okulate I, Merritt E, Bang S, Demetriou A, Li Z, Lindskrog SV, Ruan DF, Daza J, Rai R, Hegewisch-Solloa E, Mace EM, Fernandez-Rodriguez R, Izadmehr S, Doherty G, Narasimhan A, Farkas AM, Cruz-Encarnacion P, Shroff S, Patel F, Tran M, Park SJ, Qi J, Patel M, Geanon D, Kelly G, de Real RM, Lee B, Nie K, Miake-Iye S, Angeliadis K, Radkevich E, Thin TH, Garcia-Barros M, Brown H, Martin B, Mateo A, Soto A, Sussman R, Shiwlani S, Francisco-Simon S, Beaumont KG, Hu Y, Wang YC, Wang L, Sebra RP, Smith S, Skobe M, Clancy-Thompson E, Palmer D, Hammond S, Hopkins BD, Wiklund P, Zhu J, Bravo-Cordero JJ, Brody R, Hopkins B, Chen Z, Kim-Schulze S, Dyrskjøt L, Elemento O, Tocheva A, Song WM, Bhardwaj N, Galsky MD, Sfakianos JP, Horowitz A. Ranti D, et al. Among authors: elemento o. bioRxiv [Preprint]. 2024 Sep 3:2024.09.02.610816. doi: 10.1101/2024.09.02.610816. bioRxiv. 2024. PMID: 39282294 Free PMC article. Preprint.
Workshop summaries from the 2024 voice AI symposium, presented by the Bridge2AI-voice consortium.
Bahr R, Anibal J, Bedrick S, Bélisle-Pipon JC, Bensoussan Y, Blaylock N, Castermans J, Comito K, Dorr D, Hale G, Jackson C, Krussel A, Kuman K, Komarlu AR, Lerner-Ellis J, Powell M, Ravitsky V, Rameau A, Reavis C, Sigaras A, Cruz SS, Vojtech J, Urbano M, Watts S, Zhao R, Toghranegar J; Bridge2AI-Voice Consortium. Bahr R, et al. Front Digit Health. 2024 Oct 30;6:1484818. doi: 10.3389/fdgth.2024.1484818. eCollection 2024. Front Digit Health. 2024. PMID: 39540145 Free PMC article. Review.
Inhibition of Bruton's tyrosine kinase with PD-1 blockade modulates T cell activation in solid tumors.
Schwarz E, Benner B, Wesolowski R, Quiroga D, Good L, Sun SH, Savardekar H, Li J, Jung KJ, Duggan MC, Lapurga G, Shaffer J, Scarberry L, Konda B, Verschraegen C, Kendra K, Shah M, Rupert R, Monk P, Shah HA, Noonan AM, Bixel K, Hays J, Wei L, Pan X, Behbehani G, Hu Y, Elemento O, Chung D, Xin G, Blaser BW, Carson WE 3rd. Schwarz E, et al. Among authors: elemento o. JCI Insight. 2024 Nov 8;9(21):e169927. doi: 10.1172/jci.insight.169927. JCI Insight. 2024. PMID: 39513363 Free article. Clinical Trial.
The interplay of mutagenesis and ecDNA shapes urothelial cancer evolution.
Nguyen DD, Hooper WF, Liu W, Chu TR, Geiger H, Shelton JM, Shah M, Goldstein ZR, Winterkorn L, Helland A, Sigouros M, Manohar J, Moyer J, Al Assaad M, Semaan A, Cohen S, Madorsky Rowdo F, Wilkes D, Osman M, Singh RR, Sboner A, Valentine HL, Abbosh P, Tagawa ST, Nanus DM, Nauseef JT, Sternberg CN, Molina AM, Scherr D, Inghirami G, Mosquera JM, Elemento O, Robine N, Faltas BM. Nguyen DD, et al. Among authors: elemento o. Nature. 2024 Nov;635(8037):219-228. doi: 10.1038/s41586-024-07955-3. Epub 2024 Oct 9. Nature. 2024. PMID: 39385020 Free PMC article.
Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway and generates TCF1+ progenitor CD8+ T cells to improve immunotherapy.
Markowitz GJ, Ban Y, Tavarez DA, Yoffe L, Podaza E, He Y, Martin MT, Crowley MJP, Sandoval TA, Gao D, Martin ML, Elemento O, Cubillos-Ruiz JR, McGraw TE, Altorki NK, Mittal V. Markowitz GJ, et al. Among authors: elemento o. Nat Immunol. 2024 Oct;25(10):1884-1899. doi: 10.1038/s41590-024-01963-1. Epub 2024 Sep 26. Nat Immunol. 2024. PMID: 39327500
487 results