Tran TQ - Search Results

1

α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer.

Tran TQ, Hanse EA, Habowski AN, Li H, Ishak Gabra MB, Yang Y, Lowman XH, Ooi AM, Liao SY, Edwards RA, Waterman ML, Kong M. Tran TQ, et al. Nat Cancer. 2020 Mar;1(3):345-358. doi: 10.1038/s43018-020-0035-5. Epub 2020 Mar 20. Nat Cancer. 2020. PMID: 32832918 Free PMC article.

2

Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation.

Pan M, Reid MA, Lowman XH, Kulkarni RP, Tran TQ, Liu X, Yang Y, Hernandez-Davies JE, Rosales KK, Li H, Hugo W, Song C, Xu X, Schones DE, Ann DK, Gradinaru V, Lo RS, Locasale JW, Kong M. Pan M, et al. Among authors: tran tq. Nat Cell Biol. 2016 Oct;18(10):1090-101. doi: 10.1038/ncb3410. Epub 2016 Sep 12. Nat Cell Biol. 2016. PMID: 27617932 Free PMC article.

3

MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1.

Yang Y, Ishak Gabra MB, Hanse EA, Lowman XH, Tran TQ, Li H, Milman N, Liu J, Reid MA, Locasale JW, Gil Z, Kong M. Yang Y, et al. Among authors: tran tq. Nat Commun. 2019 Feb 18;10(1):809. doi: 10.1038/s41467-019-08759-0. Nat Commun. 2019. PMID: 30778058 Free PMC article.

4

Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth.

Ishak Gabra MB, Yang Y, Li H, Senapati P, Hanse EA, Lowman XH, Tran TQ, Zhang L, Doan LT, Xu X, Schones DE, Fruman DA, Kong M. Ishak Gabra MB, et al. Among authors: tran tq. Nat Commun. 2020 Jul 3;11(1):3326. doi: 10.1038/s41467-020-17181-w. Nat Commun. 2020. PMID: 32620791 Free PMC article.

5

Tumor-associated mutant p53 promotes cancer cell survival upon glutamine deprivation through p21 induction.

Tran TQ, Lowman XH, Reid MA, Mendez-Dorantes C, Pan M, Yang Y, Kong M. Tran TQ, et al. Oncogene. 2017 Apr 6;36(14):1991-2001. doi: 10.1038/onc.2016.360. Epub 2016 Oct 10. Oncogene. 2017. PMID: 27721412 Free PMC article.

6

IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3.

Reid MA, Lowman XH, Pan M, Tran TQ, Warmoes MO, Ishak Gabra MB, Yang Y, Locasale JW, Kong M. Reid MA, et al. Among authors: tran tq. Genes Dev. 2016 Aug 15;30(16):1837-51. doi: 10.1101/gad.287235.116. Epub 2016 Sep 1. Genes Dev. 2016. PMID: 27585591 Free PMC article.

7

Molecular Pathways: Metabolic Control of Histone Methylation and Gene Expression in Cancer.

Tran TQ, Lowman XH, Kong M. Tran TQ, et al. Clin Cancer Res. 2017 Aug 1;23(15):4004-4009. doi: 10.1158/1078-0432.CCR-16-2506. Epub 2017 Apr 12. Clin Cancer Res. 2017. PMID: 28404599 Free PMC article. Review.

8

Glutamine deficiency induces DNA alkylation damage and sensitizes cancer cells to alkylating agents through inhibition of ALKBH enzymes.

Tran TQ, Ishak Gabra MB, Lowman XH, Yang Y, Reid MA, Pan M, O'Connor TR, Kong M. Tran TQ, et al. PLoS Biol. 2017 Nov 6;15(11):e2002810. doi: 10.1371/journal.pbio.2002810. eCollection 2017 Nov. PLoS Biol. 2017. PMID: 29107960 Free PMC article.

9

IKKβ activates p53 to promote cancer cell adaptation to glutamine deprivation.

Ishak Gabra MB, Yang Y, Lowman XH, Reid MA, Tran TQ, Kong M. Ishak Gabra MB, et al. Among authors: tran tq. Oncogenesis. 2018 Nov 26;7(11):93. doi: 10.1038/s41389-018-0104-0. Oncogenesis. 2018. PMID: 30478303 Free PMC article.

10

p53 Promotes Cancer Cell Adaptation to Glutamine Deprivation by Upregulating Slc7a3 to Increase Arginine Uptake.

Lowman XH, Hanse EA, Yang Y, Ishak Gabra MB, Tran TQ, Li H, Kong M. Lowman XH, et al. Among authors: tran tq. Cell Rep. 2019 Mar 12;26(11):3051-3060.e4. doi: 10.1016/j.celrep.2019.02.037. Cell Rep. 2019. PMID: 30865893 Free PMC article.

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