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Page 1
HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers.
Ren S, Gaykalova DA, Guo T, Favorov AV, Fertig EJ, Tamayo P, Callejas-Valera JL, Allevato M, Gilardi M, Santos J, Fukusumi T, Sakai A, Ando M, Sadat S, Liu C, Xu G, Fisch KM, Wang Z, Molinolo AA, Gutkind JS, Ideker T, Koch WM, Califano JA. Ren S, et al. Among authors: allevato m. Oncogene. 2020 Oct;39(40):6327-6339. doi: 10.1038/s41388-020-01431-8. Epub 2020 Aug 26. Oncogene. 2020. PMID: 32848210 Free PMC article.
4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer.
Wang Z, Feng X, Molinolo AA, Martin D, Vitale-Cross L, Nohata N, Ando M, Wahba A, Amornphimoltham P, Wu X, Gilardi M, Allevato M, Wu V, Steffen DJ, Tofilon P, Sonenberg N, Califano J, Chen Q, Lippman SM, Gutkind JS. Wang Z, et al. Among authors: allevato m. Cancer Res. 2019 Apr 1;79(7):1438-1450. doi: 10.1158/0008-5472.CAN-18-1220. Epub 2019 Mar 20. Cancer Res. 2019. PMID: 30894372 Free PMC article.
Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4.
Wang Z, Wu VH, Allevato MM, Gilardi M, He Y, Luis Callejas-Valera J, Vitale-Cross L, Martin D, Amornphimoltham P, Mcdermott J, Yung BS, Goto Y, Molinolo AA, Sharabi AB, Cohen EEW, Chen Q, Lyons JG, Alexandrov LB, Gutkind JS. Wang Z, et al. Among authors: allevato mm. Nat Commun. 2019 Dec 5;10(1):5546. doi: 10.1038/s41467-019-13471-0. Nat Commun. 2019. PMID: 31804466 Free PMC article.
Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer.
Wang Z, Goto Y, Allevato MM, Wu VH, Saddawi-Konefka R, Gilardi M, Alvarado D, Yung BS, O'Farrell A, Molinolo AA, Duvvuri U, Grandis JR, Califano JA, Cohen EEW, Gutkind JS. Wang Z, et al. Among authors: allevato mm. Nat Commun. 2021 Apr 22;12(1):2383. doi: 10.1038/s41467-021-22619-w. Nat Commun. 2021. PMID: 33888713 Free PMC article.
Monomethyl auristatin antibody and peptide drug conjugates for trimodal cancer chemo-radio-immunotherapy.
Hingorani DV, Allevato MM, Camargo MF, Lesperance J, Quraishi MA, Aguilera J, Franiak-Pietryga I, Scanderbeg DJ, Wang Z, Molinolo AA, Alvarado D, Sharabi AB, Bui JD, Cohen EEW, Adams SR, Gutkind JS, Advani SJ. Hingorani DV, et al. Among authors: allevato mm. Nat Commun. 2022 Jul 5;13(1):3869. doi: 10.1038/s41467-022-31601-z. Nat Commun. 2022. PMID: 35790753 Free PMC article.
Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC.
Saddawi-Konefka R, O'Farrell A, Faraji F, Clubb L, Allevato MM, Jensen SM, Yung BS, Wang Z, Wu VH, Anang NA, Msari RA, Schokrpur S, Pietryga IF, Molinolo AA, Mesirov JP, Simon AB, Fox BA, Bui JD, Sharabi A, Cohen EEW, Califano JA, Gutkind JS. Saddawi-Konefka R, et al. Among authors: allevato mm. Nat Commun. 2022 Jul 25;13(1):4298. doi: 10.1038/s41467-022-31941-w. Nat Commun. 2022. PMID: 35879302 Free PMC article.
A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC.
Goto Y, Koshizuka K, Ando T, Izumi H, Wu X, Sato K, Ishikawa T, Ford K, Feng X, Wang Z, Arang N, Allevato MM, Kishore A, Mali P, Gutkind JS. Goto Y, et al. Among authors: allevato mm. Cancer Res Commun. 2024 Jul 1;4(7):1850-1862. doi: 10.1158/2767-9764.CRC-24-0247. Cancer Res Commun. 2024. PMID: 38954773 Free PMC article.
A genome-wide CRISPR screen reveals that antagonism of glutamine metabolism sensitizes head and neck squamous cell carcinoma to ferroptotic cell death.
Allevato MM, Trinh S, Koshizuka K, Nachmanson D, Nguyen TC, Yokoyama Y, Wu X, Andres A, Wang Z, Watrous J, Molinolo AA, Mali P, Harismendy O, Jain M, Wild R, Gutkind JS. Allevato MM, et al. Cancer Lett. 2024 Aug 28;598:217089. doi: 10.1016/j.canlet.2024.217089. Epub 2024 Jul 2. Cancer Lett. 2024. PMID: 38964731
35 results