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Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics.
Akinci E, Cha M, Lin L, Yeo G, Hamilton MC, Donahue CJ, Bermudez-Cabrera HC, Zanetti LC, Chen M, Barkal SA, Khowpinitchai B, Chu N, Velimirovic M, Jodhani R, Fife JD, Sovrovic M, Cole PA, Davey RA, Cassa CA, Sherwood RI. Akinci E, et al. Among authors: cassa ca. bioRxiv [Preprint]. 2020 Aug 28:2020.08.27.270819. doi: 10.1101/2020.08.27.270819. bioRxiv. 2020. PMID: 32869031 Free PMC article. Preprint.
Systematic elucidation of genetic mechanisms underlying cholesterol uptake.
Hamilton MC, Fife JD, Akinci E, Yu T, Khowpinitchai B, Cha M, Barkal S, Thi TT, Yeo GHT, Ramos Barroso JP, Jake Francoeur M, Velimirovic M, Gifford DK, Lettre G, Yu H, Cassa CA, Sherwood RI. Hamilton MC, et al. Among authors: cassa ca. bioRxiv [Preprint]. 2023 Jan 10:2023.01.09.500804. doi: 10.1101/2023.01.09.500804. bioRxiv. 2023. Update in: Cell Genom. 2023 Apr 21;3(5):100304. doi: 10.1016/j.xgen.2023.100304 PMID: 36711952 Free PMC article. Updated. Preprint.
Systematic elucidation of genetic mechanisms underlying cholesterol uptake.
Hamilton MC, Fife JD, Akinci E, Yu T, Khowpinitchai B, Cha M, Barkal S, Thi TT, Yeo GHT, Ramos Barroso JP, Francoeur MJ, Velimirovic M, Gifford DK, Lettre G, Yu H, Cassa CA, Sherwood RI. Hamilton MC, et al. Among authors: cassa ca. Cell Genom. 2023 Apr 21;3(5):100304. doi: 10.1016/j.xgen.2023.100304. eCollection 2023 May 10. Cell Genom. 2023. PMID: 37228746 Free PMC article.
Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification.
Ryu J, Barkal S, Yu T, Jankowiak M, Zhou Y, Francoeur M, Phan QV, Li Z, Tognon M, Brown L, Love MI, Lettre G, Ascher DB, Cassa CA, Sherwood RI, Pinello L. Ryu J, et al. Among authors: cassa ca. medRxiv [Preprint]. 2023 Sep 10:2023.09.08.23295253. doi: 10.1101/2023.09.08.23295253. medRxiv. 2023. Update in: Nat Genet. 2024 May;56(5):925-937. doi: 10.1038/s41588-024-01726-6 PMID: 37732177 Free PMC article. Updated. Preprint.
51 results