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Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics.
Akinci E, Cha M, Lin L, Yeo G, Hamilton MC, Donahue CJ, Bermudez-Cabrera HC, Zanetti LC, Chen M, Barkal SA, Khowpinitchai B, Chu N, Velimirovic M, Jodhani R, Fife JD, Sovrovic M, Cole PA, Davey RA, Cassa CA, Sherwood RI. Akinci E, et al. Among authors: chu n. bioRxiv [Preprint]. 2020 Aug 28:2020.08.27.270819. doi: 10.1101/2020.08.27.270819. bioRxiv. 2020. PMID: 32869031 Free PMC article. Preprint.
Switching immune signals on and off.
Chu N, Cole PA. Chu N, et al. Elife. 2015 Apr 2;4:e07204. doi: 10.7554/eLife.07204. Elife. 2015. PMID: 25838130 Free PMC article.
AKTivation mechanisms.
Cole PA, Chu N, Salguero AL, Bae H. Cole PA, et al. Among authors: chu n. Curr Opin Struct Biol. 2019 Dec;59:47-53. doi: 10.1016/j.sbi.2019.02.004. Epub 2019 Mar 20. Curr Opin Struct Biol. 2019. PMID: 30901610 Free PMC article. Review.
The protein kinase Akt acts as a coat adaptor in endocytic recycling.
Hsu JW, Bai M, Li K, Yang JS, Chu N, Cole PA, Eck MJ, Li J, Hsu VW. Hsu JW, et al. Among authors: chu n. Nat Cell Biol. 2020 Aug;22(8):927-933. doi: 10.1038/s41556-020-0530-z. Epub 2020 Jun 15. Nat Cell Biol. 2020. PMID: 32541877 Free PMC article.
Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications.
Salguero AL, Chen M, Balana AT, Chu N, Jiang H, Palanski BA, Bae H, Wright KM, Nathan S, Zhu H, Gabelli SB, Pratt MR, Cole PA. Salguero AL, et al. Among authors: chu n. ACS Chem Biol. 2022 Jan 21;17(1):68-76. doi: 10.1021/acschembio.1c00632. Epub 2021 Dec 23. ACS Chem Biol. 2022. PMID: 34941261 Free PMC article.
Enzyme-catalyzed expressed protein ligation.
Henager SH, Chu N, Chen Z, Bolduc D, Dempsey DR, Hwang Y, Wells J, Cole PA. Henager SH, et al. Among authors: chu n. Nat Methods. 2016 Nov;13(11):925-927. doi: 10.1038/nmeth.4004. Epub 2016 Sep 26. Nat Methods. 2016. PMID: 27669326 Free PMC article.
Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis.
Chu N, Salguero AL, Liu AZ, Chen Z, Dempsey DR, Ficarro SB, Alexander WM, Marto JA, Li Y, Amzel LM, Gabelli SB, Cole PA. Chu N, et al. Cell. 2018 Aug 9;174(4):897-907.e14. doi: 10.1016/j.cell.2018.07.003. Epub 2018 Aug 2. Cell. 2018. PMID: 30078705 Free PMC article.
892 results