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Rejection of intestinal allotransplants is driven by memory T helper type 17 immunity and responds to infliximab.
Kroemer A, Belyayev L, Khan K, Loh K, Kang J, Duttargi A, Dhani H, Sadat M, Aguirre O, Gusev Y, Bhuvaneshwar K, Kallakury B, Cosentino C, Houlihan B, Diaz J, Moturi S, Yazigi N, Kaufman S, Subramanian S, Hawksworth J, Girlanda R, Robson SC, Matsumoto CS, Zasloff M, Fishbein TM. Kroemer A, et al. Among authors: loh k. Am J Transplant. 2021 Mar;21(3):1238-1254. doi: 10.1111/ajt.16283. Epub 2020 Sep 25. Am J Transplant. 2021. PMID: 32882110 Free PMC article.
Type 3 innate lymphoid cells are associated with a successful intestinal transplant.
Kang J, Loh K, Belyayev L, Cha P, Sadat M, Khan K, Gusev Y, Bhuvaneshwar K, Ressom H, Moturi S, Kaiser J, Hawksworth J, Robson SC, Matsumoto CS, Zasloff M, Fishbein TM, Kroemer A. Kang J, et al. Among authors: loh k. Am J Transplant. 2021 Feb;21(2):787-797. doi: 10.1111/ajt.16163. Epub 2020 Jul 21. Am J Transplant. 2021. PMID: 32594614 Free PMC article.
Immunologic Complications and Graft Survival in Crohn's Disease and NOD2 Mutant Non-Crohn's Disease Adult Recipients Following Intestine Transplantation.
Belyayev L, Hawksworth J, Khan K, Kaufman S, Subramanian S, Kroemer A, Loh K, Girlanda R, Fishbein TM, Matsumoto CS. Belyayev L, et al. Among authors: loh k. Transplant Direct. 2020 May 21;6(6):e556. doi: 10.1097/TXD.0000000000001006. eCollection 2020 Jun. Transplant Direct. 2020. PMID: 32607422 Free PMC article.
Oral N-acetylcysteine decreases IFN-γ production and ameliorates ischemia-reperfusion injury in steatotic livers.
Liggett JR, Kang J, Ranjit S, Rodriguez O, Loh K, Patil D, Cui Y, Duttargi A, Nguyen S, He B, Lee Y, Oza K, Frank BS, Kwon D, Li HH, Kallakury B, Libby A, Levi M, Robson SC, Fishbein TM, Cui W, Albanese C, Khan K, Kroemer A. Liggett JR, et al. Among authors: loh k. Front Immunol. 2022 Sep 5;13:898799. doi: 10.3389/fimmu.2022.898799. eCollection 2022. Front Immunol. 2022. PMID: 36148239 Free PMC article.
Suppressor T helper type 17 cell responses in intestinal transplant recipients with allograft rejection.
Belyayev L, Kang J, Sadat M, Loh K, Patil D, Muralidaran V, Khan K, Kaufman S, Subramanian S, Gusev Y, Bhuvaneshwar K, Ressom H, Varghese R, Ekong U, Matsumoto CS, Robson SC, Fishbein TM, Kroemer A. Belyayev L, et al. Among authors: loh k. Hum Immunol. 2024 May;85(3):110773. doi: 10.1016/j.humimm.2024.110773. Epub 2024 Mar 16. Hum Immunol. 2024. PMID: 38494386
DNMT3AR882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency.
Koehnke T, Karigane D, Hilgart E, Fan AC, Kayamori K, Miyauchi M, Collins CT, Suchy FP, Rangavajhula A, Feng Y, Nakauchi Y, Martinez-Montes E, Fowler J, Loh KM, Nakauchi H, Koldobskiy MA, Feinberg AP, Majeti R. Koehnke T, et al. Among authors: loh km. bioRxiv [Preprint]. 2024 Oct 29:2024.10.26.620318. doi: 10.1101/2024.10.26.620318. bioRxiv. 2024. PMID: 39553934 Free PMC article. Preprint.
1,219 results